Results 231 to 240 of about 503,882 (291)
Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
Here, we introduce a molecular design principle that fundamentally expands the bottom‐up synthesis of single‐atom catalysts (SACs). Coordinatively flexible polypyridyl units enable bottom‐up formation of ordered carbonaceous frameworks containing atomically dispersed Ru (∼11 wt%) by simple carbonization.
Koki Chida +13 more
wiley +2 more sources
Bone Anabolic Treatment in Patients With Chronic Kidney Disease: A Systematic Review. [PDF]
Kafa HS, Hauge SC, Hansen D.
europepmc +1 more source
β‐C(sp3)—H Arylierung Aliphatischer Sulfonamide
Das erste Protokoll zur β‐C(sp3)—H‐Aktivierung/Funktionalisierung aliphatischer Sulfonamide wird beschrieben. Die Arylierung solcher Substrate wird durch den Einsatz von N‐Acetylthioether‐Liganden ermöglicht und zeichnet sich durch ein breites Substratspektrum sowohl hinsichtlich des Sulfonamid‐Substrats als auch des Arylierungsreagenzes aus.
Friedrich Jurk +2 more
wiley +1 more source
A randomised, open-label, phase II study of tobemstomig combinations in patients with previously untreated advanced clear-cell renal cell carcinoma. [PDF]
Rini BI +17 more
europepmc +1 more source
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini +13 more
wiley +1 more source
Image-guided moderately hypofractionated proton beam therapy for localized prostate cancer: 5-year outcomes of a phase II trial. [PDF]
Iizumi T +13 more
europepmc +1 more source

