Results 31 to 40 of about 434,441 (275)

Incidence and time course of everolimus-related adverse events in postmenopausal women with hormone receptor-positive advanced breast cancer: insights from BOLERO-2. [PDF]

, 2014
BackgroundIn the BOLERO-2 trial, everolimus (EVE), an inhibitor of mammalian target of rapamycin, demonstrated significant clinical benefit with an acceptable safety profile when administered with exemestane (EXE) in postmenopausal women with hormone ...
Baselga, J, Bauly, H, Burris, HA, Chouinard, E, Csoszi, T, Eakle, J, El-Hashimy, M, Feng, W, Geberth, M, Gnant, M, Hortobagyi, G, Noguchi, S, Perez, A, Piccart, M, Pritchard, KI, Puttawibul, P, Rugo, HS, Srimuninnimit, V, Taran, T   +18 more
core   +1 more source

A step towards digital transformation within a utility company through process automation for a sustainable energy transition

The Journal of Engineering
Sustainable energy management systems are part of the global energy transition by digitally transforming utility companies throughout the past decade. Industry 4.0 (4IR) has been adopted to improve competitiveness and align its processes with trends that
Nhora Parra, Sandra Giraldo, David laRotta, Betsy Gómez, Yissel Mejía, Laidi Morales, César Nieto‐Londoño, Rafael E. Vásquez   +7 more
doaj   +1 more source

Empirical evaluation of an adaptive e-learning system and the effects of knowledge, learning styles and multimedia mode on student achievement [PDF]

, 2007
This paper presents an empirical evaluation of an adaptive e-learning system (AES). The system was evaluated in an experimental research. During the 9 weeks of experimentation, the students studied the learning material in two randomly allocated groups ...
Surjono, Herman Dwi
core  

AES-CBC Software Execution Optimization

, 2012
With the proliferation of high-speed wireless networking, the necessity for efficient, robust and secure encryption modes is ever increasing. But, cryptography is primarily a computationally intensive process.
Doma, Jayramsingh, Doomun, Razvi, Tengur, Sundeep   +2 more
core   +1 more source

Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens. [PDF]

, 2014
PurposeWe sought to compare the economic impact of treatment-related adverse events (AEs) in patients with metastatic breast cancer (mBC) using taxane- or capecitabine-based treatment regimens as either first- or second-line (FL or SL) therapy in the US ...
Brammer, Melissa, Hansen, Ryan N, Hurvitz, Sara A, Kamath, Tripthi, Lalla, Deepa, Masaquel, Anthony, Ramsey, Scott D, Sullivan, Sean D   +7 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Sustainable trophy hunting and the conservation of alpine ungulates in Pakistan

Pirineos: Revista de Ecología de Montaña, 2002
[fr] Au nord du Pakistan, les ongulés alpins se distribuent dans des habitats diversifiés mais leur nombre a diminué ces dernières décades, peut-être du fait du braconnage et de la dégradation de l'habitat par les troupeaux domestiques.
M. Arshald, R. J. Garson, A. Ahmad
doaj   +1 more source

CacheZoom: How SGX Amplifies The Power of Cache Attacks [PDF]

, 2017
In modern computing environments, hardware resources are commonly shared, and parallel computation is widely used. Parallel tasks can cause privacy and security problems if proper isolation is not enforced.
D Brumley, D Gruss, DA Osvik, DJ Bernstein, G Irazoqui, J Bonneau, M Hamburg, M Matsui, MS İnci, N Benger, N Weichbrodt, O Acıiçmez, PC Kocher, R Langner, S Bhattacharya, T Morris, Y Tsunoo   +16 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Identification of Adzuki Bean Quantitative Trait Loci Associated With Resistance to Soybean Cyst Nematode

Legume Science
Soybean cyst nematode (SCN; Heterodera glycines Ichinohe) infection has recently been shown to cause yield loss in adzuki bean (Vigna angularis [Willd.] Ohwi & Ohashi).
Chihiro Souma, Takashi Todai, Fumiko Kousaka, Hidetaka Nagasawa, Reina Ogura, Takako Suzuki   +5 more
doaj   +1 more source