Results 31 to 40 of about 857 (144)

Pathologic substrate of gastropathy in Anderson-Fabry disease

Orphanet Journal of Rare Diseases, 2020
In both classic and late-onset AFD, mutations of the GLA gene cause deficient activity of the alpha-galactosidase enzyme resulting in intracellular accumulation of the undigested substrate.
Alessandro Di Toro, Nupoor Narula, Lorenzo Giuliani, Monica Concardi, Alexandra Smirnova, Valentina Favalli, Mario Urtis, Costanza Alvisi, Elena Antoniazzi, Eloisa Arbustini   +9 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

“We Are Willing to Change, If…”: Potential Impacts of Citizens' Assemblies on the Willingness to Change for Sustainability in Rural East German Municipalities

Environmental Policy and Governance, EarlyView.
ABSTRACT In light of the democratic and social‐ecological crises, deliberative minipublics such as citizens' assemblies are increasingly implemented and discussed by scholars as a means for sound decision‐making and to enhance public support for sustainability transformations.
Lea Findeis, Nicolas Jager
wiley   +1 more source

Politische Engagementbereitschaft in Krisenszenarien : AfD-Parteiverbot vs AfD-Regierungsbeteiligung

Die Debatte über ein mögliches Parteiverbot der AfD sowie über eine potenzielle Regierungsbeteiligung der Partei wird in Politik und Medien regelmäßig aufgegriffen – etwa im Zusammenhang mit umstrittenen Reden von AfD-Politiker:innen, Einstufungen der Verfassungsschutzbehörden, einschlägigen Gerichtsentscheidungen oder Wahlkämpfen.
Stolle, Paula, Hajji, Rahim, Quent, Matthias   +2 more
openaire   +3 more sources

Radicalized by TikTok and Co.? The Influence of Social Media Use on Far-Right Orientations of Young Adults in Germany

Zeitschrift für Rechtsextremismusforschung
Right-wing extremism among young people often gets attributed to radicalisation on social media. This study examines how the use of various social media platforms affects extremist-leaning attitudes of young people in Germany.
Matthias Quent, Christian Stein
doaj   +1 more source

Cardiovascular magnetic resonance native T1 mapping in Anderson-Fabry disease: a systematic review and meta-analysis

Journal of Cardiovascular Magnetic Resonance, 2022
Background T1 mapping is an established cardiovascular magnetic resonance (CMR) technique that can characterize myocardial tissue. We aimed to determine the weighted mean native T1 values of Anderson-Fabry disease (AFD) patients and the standardized mean
Andrea Ponsiglione, Michele Gambardella, Roberta Green, Valeria Cantoni, Carmela Nappi, Raffaele Ascione, Marco De Giorgi, Renato Cuocolo, Antonio Pisani, Mario Petretta, Alberto Cuocolo, Massimo Imbriaco   +11 more
doaj   +1 more source

Right Ventricular Myocardial Involvement in Anderson–Fabry Disease at Diagnosis: Evaluation with Three-Dimensional Strain Imaging

Life, 2023
Background: Right ventricular (RV) involvement in Anderson–Fabry disease (AFD) is well known in the advanced stages of the disease RV hypertrophies, but little is known about the early involvement.
Martina Pucci, Velia Iadevaia, Vittoria Gammaldi, Adelaide Iervolino, Luca Maria Capece, Domenico Sciascia, Vittoria Cuomo, Marina Iacono, Daniele Paoletta, Ciro Santoro, Roberta Esposito   +10 more
doaj   +1 more source

From Empire to Aid: Analysing Persistence of Colonial Legacies in Foreign Aid to Africa

Journal of International Development, EarlyView.
ABSTRACT For decades now, Western development agencies and donors have been castigated for their colonial biases in providing aid to Africa. It is well established that donors provide considerably more foreign aid to their former colonies relative to other countries.
Swetha Ramachandran
wiley   +1 more source

Lokale Repräsentationsspezifika der AfD im Vergleich: Klassenfragen im Kontext der sachsen-anhaltinischen Kommunalwahl 2024

Zeitschrift für Rechtsextremismusforschung
In diesem Artikel werden deskriptive Repräsentationsmuster und -disparitäten der AfD auf kommunaler Ebene am Fallbeispiel der sachsen-anhaltinischen Kommunalwahlen 2024 herausgearbeitet.
Nikolas Dietze
doaj   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source