Results 71 to 80 of about 4,317,587 (273)

Linguistische Analyse von Emotionen am Beispiel der polnischen und deutschen Boulevardpresse

open access: yesColloquia Germanica Stetinensia
The article presents the results of an analysis of emotions that is mainly based on the assumptions of discourse linguistics and partly also of media linguistics.
Sławomir Kowalewski
doaj   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao   +10 more
wiley   +1 more source

THE APPRAISAL ANALYSIS OF CHARACTER IN RESOLUTION PART OF THE OLD MAN AND THE SEA BY ERNEST HEMINGWAY

open access: yesELTALL, 2020
This research aimed to analyze the character of Santiago in resolution part of the novel “The Old Man and The Sea” by Ernest Hemingway using SFL Appraisal Theory.
Kadek Sonia Piscayanti
doaj   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

LANGUAGE MEANS OF EXPRESSIVENESS IN ENGLISH BUSINESS-TWITTER

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2020
The scientific novelty of this article lies in the attempt to highlight the characteristic frequency mechanisms of linguistic creativity of business users of microblog Twitter, such as abbreviation, neologization, reformalization, blending, expressive ...
Elena Anatolevna Goncharova
doaj   +1 more source

The Role of Actual and Purported Origin in e‐Commerce Wine Pricing: Evidence From Italian and French Names on Labels

open access: yesAgribusiness, EarlyView.
ABSTRACT The origin of a product, if associated with good quality, can contribute to building a positive collective reputation, leading to a potential price premium. However, it is conceivable that a producer markets a product by evoking symbols, images, words, and values typical of places other than where it was designed or produced, creating a ...
Annalisa Caloffi   +2 more
wiley   +1 more source

Metaphors in Wine-tasting Notes in English and Spanish. El lenguaje metafórico en las fichas de cata de vino en inglés y en español

open access: yesHermeneus, 2019
Conceptual metaphor in cognitive linguistics involves understanding one semantic domain in terms of the other. Conceptual associations between domains have been considered universal, unidirectional and usage-based. However, the concept
BELÉN LÓPEZ ARROYO
doaj   +1 more source

Consumer Preferences for Craft Beer: The Interplay of Localness and Advertising Language

open access: yesAgribusiness, EarlyView.
ABSTRACT This study explores the influence of the language of the label, origin of production, and origin of brewing ingredients on Croatian consumers' preferences and willingness to pay for organic craft beer. Employing an online survey and a choice experiment among 223 Croatian alcohol consumers, we find that while there's a willingness to pay a ...
Marija Cerjak   +2 more
wiley   +1 more source

Teacher Autonomy: A Critical Review of the Research and Concept beyond Applied Linguistics

open access: yesIkala: Revista de Lenguaje y Cultura, 2007
In this paper I will review conceptual and empirical research on teacher autonomy beyond the limits of applied linguistics. Research shows that teacher autonomy can be conceptualized as a personal sense of freedom from interference or in terms of ...
Jaime Usma Wilches
doaj  

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