Results 111 to 120 of about 1,367,904 (292)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Shared Skin: The Slow Intimacy of Horse and Rider [PDF]
Feminist Encounters: A Journal of Critical Studies in Culture and PoliticsThis essay explores the co-constructed sensory experiences between two species over time, offering a deeper understanding both of the multi-sensory nature and different scales of inter-species intimacy. A five millennia long intimate sensory conversation
Sandra Swart
doaj +1 more source
A POMDP approach to Affective Dialogue Modeling [PDF]
, 2007 We propose a novel approach to developing a dialogue model that is able to take into account some aspects of the user's affective state and to act appropriately.
Bui, Trung H. +3 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The impact of working conditions on commitment of academic employees: A socio-affective perspective [PDF]
Problems and Perspectives in ManagementAcademic employees face declining working conditions that may reduce the level of commitment to resource-constrained public higher education institutions.
Baphiwe Daweti +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Affective Decision Making and the Ellsberg Paradox [PDF]
Affective decision-making is a strategic model of choice under risk and uncertainty where we posit two cognitive processes -- the "rational" and the "emotional" process. Observed choice is the result of equilibrium in this intrapersonal game.
Anat Bracha, Donald J. Brown
core
Structural balance emerges and explains performance in risky decision-making. [PDF]
, 2019 Polarization affects many forms of social organization. A key issue focuses on which affective relationships are prone to change and how their change relates to performance.
Askarisichani, Omid +5 more
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Amfiteatru Economic, 2015 Currently, most markets are characterized by high competition among shopping centers. Under these circumstances, the evolution in the competitiveness and performance of the centers is increasingly linked to the success in the innovation of current ...
Ioana-Nicoleta Abrudan +2 more
doaj