Results 111 to 120 of about 1,377,205 (292)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Come, see and experience affective interactive art [PDF]

, 2009
The progress in the field of affective computing enables the realization of affective consumer products, affective games, and affective art. This paper describes the affective interactive art system Mood Swings, which interprets and visualizes affect ...
Bialoskorski, Leticia S.S., Broek, Egon L. van den, Westerink, Joyce H.D.M.   +2 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Biblical Perspective and Educational Domains in Sex Education: Addressing Gaps in Indonesian Sex Education

Dunamis: Jurnal Teologi dan Pendidikan Kristiani
In Indonesia, sex education is delivered in public high schools as part of the biology curriculum and under the topic of reproductive health. According to the government’s view, when schools teach students properly about reproductive health, they will ...
Esther Idayanti, Jimmy Boaz Oentoro, Frans Silalahi   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Between financial, environmental and health concerns: the role of risk perceptions in modeling efuel acceptance

Frontiers in Energy Research
The transition towards sustainable and defossilized mobility systems relies on public perception and acceptance of innovations like efuels. Understanding the role of risk perceptions and their different dimensions in shaping public acceptance is ...
Katrin Arning, Julia Offermann, Linda Engelmann, Regina Gimpel, Martina Ziefle   +4 more
doaj   +1 more source

Structural balance emerges and explains performance in risky decision-making. [PDF]

, 2019
Polarization affects many forms of social organization. A key issue focuses on which affective relationships are prone to change and how their change relates to performance.
Askarisichani, Omid, Bullo, Francesco, Friedkin, Noah E, Lane, Jacqueline Ng, Singh, Ambuj K, Uzzi, Brian   +5 more
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Analisis Hasil Pembelajaran Matematika pada Ranah Afektif Mahasiswa Calon Guru di IAIN Purwokerto

INSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2017
Like other lessons, mathematics has learning objectives in affective domain besides in cognitive and psychomotor domain. Formally, this can be seen in the formulation of the objectives of mathematics learning, as stated in the curriculum. The success of
Maria Ulpah
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source