Results 181 to 190 of about 335,963 (286)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

How Psychological Wellbeing and Digital Mental Health Services Intervene the Role of Self-Efficacy and Affective Commitment of University Students in Their Performance? [PDF]

Front Psychiatry, 2022
Min W, Jun G, Feng L.
europepmc   +1 more source

Six types of psychological contracts: their affective commitment and employability. [PDF]

The purpose of this study is to identify a variety of employment relationships based upon an economy-wide, representative sample. We turn to psychological contract studies examining different types of psychological contracts.
Janssens, Maddy, Sels, Luc, Van den Brande, Inge   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Ethical Climate, Intrinsic Motivation, and Affective Commitment: The Impact of Depersonalization. [PDF]

Eur J Investig Health Psychol Educ
Carlos ST, Yirsa JP, Elisenda TP.
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Moderating Effects of Telework Intensity on the Relationship Between Ethical Climate, Affective Commitment and Burnout in the Colombian Electricity Sector Amid the COVID-19 Pandemic. [PDF]

Behav Sci (Basel)
Santiago-Torner C.
europepmc   +1 more source

Building Innovative Teams: Exploring the Positive Contribute of Emotions Expression and Affective Commitment. [PDF]

Front Psychol, 2021
Damasceno R, Dimas ID, Lourenço PR, Rebelo T, Alves MP.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

What Turns Task Crafters into High Performers? Affective Commitment and Strategic Alignment as Critical Levers. [PDF]

Behav Sci (Basel)
Shin I, Park JG, Chae H.
europepmc   +1 more source