Results 261 to 270 of about 40,297 (307)

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Understanding Affective Organizational Commitment

American Review of Public Administration, 2011
This study proposes and tests a model of affective organizational commitment that seeks to capture aspects of the unique institutional context of public organizations. An analysis of survey data from seven public sector organizations suggests external control increases organizational goal ambiguity and two types of bureaucratic red tape, which, in turn,
Edmund C Stazyk, Sanjay K Pandey, Bradley E Wright   +2 more
exaly   +3 more sources

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Affective Commitment as a Core Essence of Organizational Commitment

Human Resource Development Review, 2015
This article responds to the call for the identification of a core essence of organizational commitment. Since this call 14 years ago, scholars studying organizational commitment have not come to an agreement as to the nature of organizational commitment, and how it develops.
exaly   +2 more sources

Affective Commitment to Congregations

Pastoral Psychology, 2011
This study identified four multidimensional factors that significantly influence affective commitment of church members to their congregations. The sample (N = 382) consisted of members of three congregations: Unitarian Universalist (UU), United Methodist (UMC), and Evangelical Free Church (EFC).
Jai Ghorpade, James R. Lackritz, Rebecca Moore   +2 more
openaire   +1 more source

On the Elusive Moderators of Affective Organizational Commitment

The Spanish Journal of Psychology, 2021
AbstractDeparting from a universal perspective on affective organizational commitment, the present article examines the situational and personal variables that act as potential moderators of the relationship between affective commitment and its antecedents and outcomes.
openaire   +2 more sources

Organizational Identification and Commitment: Correlates of Sense of Belonging and Affective Commitment

The Spanish journal of psychology, 2012
The general purpose of this work is to analyze the overlap between organizational identification and commitment. Specifically, our study focuses on the analysis of the differences and similarities between sense of belonging (a dimension of organizational identification) and affective commitment (a dimension of organizational commitment). In order to do
Ma Celeste, Dávila, Gemma, Jiménez García   +1 more
openaire   +2 more sources

Affective commitment in the public sector

Proceedings of the 2006 ACM SIGMIS CPR conference on computer personnel research: Forty four years of computer personnel research: achievements, challenges & the future, 2006
To improve our understanding of individual motivations to remain employed in governmental agencies this study focuses on a specific segment of a state government agency workforce. Information technology (IT) employees possess skills that transfer easily to other sectors, which make them an important group when examining factors that influence the ...
Margaret F. Reid, Myria W. Allen, Cynthia K. Riemenschneider, Deborah J. Armstrong   +3 more
openaire   +1 more source

Commitment and employee behavior: Comparison of affective commitment and continuance commitment with perceived organizational support.

Journal of Applied Psychology, 1993
The social exchange view of commitment (R. Eisenberger, R. Huntington, S. Hutchison, & D. Sowa, 1986) suggests that employees' perceptions of the organization's commitment to them (perceived organizational support, or POS) creates feelings of obligation to the employer, which enhances employees' work behavior.
L M, Shore, S J, Wayne
openaire   +2 more sources