Results 81 to 90 of about 466,251 (333)

The relationship between cognitive and affective control and symptoms of depression and anxiety across the lifespan: A 3-wave longitudinal study

open access: yesComprehensive Psychiatry
Introduction: The association between cognitive functioning and mental health symptoms across the lifespan remains poorly understood. Understanding the directionality of the association between mental health and cognition is important as most gold ...
Anson Kai Chun Chau   +3 more
doaj   +1 more source

An initial investigation of the role of depressive and anxious syndromes in Problematic Internet Use in adolescence and young adults

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2023
Depressive and anxious syndromes have been proposed as risk factors and as consequences of Problematic Internet Use (PIU). There has been no study relating affective symptoms in subjects with Problematic Internet Use and those with major depressive and ...
Sofia Botelho de Sousa Paulino   +4 more
doaj   +1 more source

Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework [PDF]

open access: yes, 2010
We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings.
De Raedt, Rudi, Koster, Ernst
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Association between depressive symptom clusters and food attentional bias [PDF]

open access: yes, 2018
Background The mechanisms underlying the depression-obesity relationship are unclear. Food attentional bias (FAB) represents one candidate mechanism that has not been examined.
Ciciolla, Lucia   +5 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

The comparison attachment styles and Alexithymia in suicidal attempts and control group [PDF]

open access: yesروانشناسی و روانپزشکی شناخت, 2020
Introduction: Suicide can be defined as a conscious act of self-harm that leads to death. Aim: The aim of this study was to comparison attachment styles and alexithymia in suicidal attempts and control group. Method: In this casual comparative study,
Maryam Ghorbani, Maryam Najafi
doaj  

The effectiveness of the unified protocol on symptoms, quality of life, negative affect, and negative reactivity in irritable bowel syndrome patients in comorbidity with anxiety and depression [PDF]

open access: bronze, 2022
Ala Ghapanchi   +5 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

The Intricate Relationship between Psychotic-Like Experiences and Associated Subclinical Symptoms in Healthy Individuals

open access: yesFrontiers in Psychology, 2017
The interplay between subclinical psychotic, negative, and affective symptoms has gained increased attention regarding the etiology of psychosis spectrum and other mental disorders.
Lui Unterrassner   +7 more
doaj   +1 more source

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