Results 91 to 100 of about 144,513 (307)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Dirac cohomology for the degenerate affine Hecke Clifford algebra [PDF]
, 2015 We define an analogue of the Dirac operator for the degenerate affine Hecke-Clifford algebra. A main result is to relate the central characters of the degenerate affine Hecke-Clifford algebra with the central characters of the Sergeev algebra via Dirac ...
Chan, Kei Yuen
core
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Point Cloud Registration in Multidirectional Affine Transformation
IEEE Photonics Journal, 2018 Point clouds scanned by three-dimensional lasers may be multidirectional affine transformed when the specifications for the products, laser scanners, and thermal expansion are incompatible.
Chang Wang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source
Improvement of affine iterative closest point algorithm for partial registration
IET Computer Vision, 2017 In this study, partial registration problem with outliers and missing data in the affine case is discussed. To solve this problem, a novel objective function is proposed based on bidirectional distance and trimmed strategy, and then a new affine trimmed ...
Jianmin Dong, Zhongmin Cai, Shaoyi Du
doaj +1 more source
Radon transforms on affine Grassmannians [PDF]
Transactions of the American Mathematical Society, 2004 We develop an analytic approach to the Radon transform f ^ ( ζ ) = ∫ τ ⊂ ζ f ( τ ) \hat f (\zeta )=\int _{\tau \subset \zeta } f (\tau ) , where ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source