Results 61 to 70 of about 18,923 (306)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

3D Convex Hull-Based Registration Method for Point Cloud Watermark Extraction

Sensors, 2019
Most 3D point cloud watermarking techniques apply Principal Component Analysis (PCA) to protect the watermark against affine transformation attacks. Unfortunately, they fail in the case of cropping and random point removal attacks.
Bogdan Lipuš, Borut Žalik
doaj   +1 more source

CAISOV: Collinear Affine Invariance and Scale-Orientation Voting for Reliable Feature Matching

Remote Sensing, 2022
Reliable feature matching plays an important role in the fields of computer vision and photogrammetry. Due to the complex transformation model caused by photometric and geometric deformations, and the limited discriminative power of local feature ...
Haihan Luo, Kai Liu, San Jiang, Qingquan Li, Lizhe Wang, Wanshou Jiang   +5 more
doaj   +1 more source

On quasi-affine transforms of Read’s operator [PDF]

Proceedings of the American Mathematical Society, 2002
We show that C. J. Read’s example of an operator T T on ℓ 1 \ell _1 which does not have any non-trivial invariant subspaces is not the adjoint of an operator on a predual of ℓ 1 \ell _1 .
Thomas Schlumprecht, Vladimir G. Troitsky   +1 more
openaire   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Quantum deformation of the affine transformation algebra [PDF]

Physics Letters A, 1994
We discuss quantum deformation of the affine transformation algebra. It is shown that the quantum algebra has a non-cocommutative Hopf algebra structure, simple realizations and quantum tensor operators.
Haru-Tada Sato, Naruhiko Aizawa
openaire   +3 more sources

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Practically Lossless Affine Image Transformation

IEEE Transactions on Image Processing, 2020
In this contribution we introduce an almost lossless affine 2D image transformation method. To this end we extend the theory of the well-known Chirp-z transform to allow for fully affine transformation of general n-dimensional images. In addition we give a practical spatial and spectral zero-padding approach dramatically reducing losses of our ...
Daniel Pflugfelder, Hanno Scharr
openaire   +4 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source