Results 61 to 70 of about 2,193,626 (355)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Confinement-induced columnar crystals of ellipses

open access: yesPhysical Review Research, 2021
Densest-packed structures of identical ellipses within a parallel strip have been obtained through Monte Carlo simulations and analytic derivations. Each of such structures is an affine transformation of a particular densest-packed structure of identical
Weiwei Jin (金炜炜)   +3 more
doaj   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

Maxwell-affine gauge theory of gravity

open access: yesPhysics Letters B, 2015
The Maxwell extension of the affine algebra in four dimensions with additional tensor generator is given. Using the methods of nonlinear realizations, we find the transformation rules for the group parameters and the corresponding generators. Gauging the
O. Cebecioğlu, S. Kibaroğlu
doaj   +1 more source

Affine Shape Comparison using Different Distances

open access: yesJOIV: International Journal on Informatics Visualization, 2020
In this work, we propose to compare affine shape using Hausdorff distance (HD), Dynamic Time Warping (DTW), Frechet (DF), and Earth Mover distance (EMD).
Khalid Aznag   +3 more
doaj   +1 more source

ROBUST MOSAICKING OF UAV IMAGES WITH NARROW OVERLAPS [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
This paper considers fast and robust mosaicking of UAV images under a circumstance that each UAV images have very narrow overlaps in-between. Image transformation for image mosaicking consists of two estimations: relative transformations and global ...
J. Kim, T. Kim, D. Shin, S. H. Kim
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

GO-APSR: A Globally Optimal Affine Point Set Registration Method

open access: yesIEEE Access, 2019
Point set registration under affine transformation is an important problem in computer vision because not only it has many direct applications, but it is also often used as an initial step for non-rigid registration.
Xuechen Li   +3 more
doaj   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

On Affine Transformations of a Riemannian Manifold [PDF]

open access: yesNagoya Mathematical Journal, 1955
In this paper we establish some theorems about the group of affine transformations on a Riemannian manifold. First we prove a decomposition theorem (Theorem 1) of the largest connected group of affine transformations on a simply connected complete Riemannian manifold, which corresponds to the decomposition theorem of de Rham [4] for the manifold.
openaire   +2 more sources

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