Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
A physics-informed graph neural network to approximate docking-based binding affinity for DYRK2 in Alzheimer's drug repurposing. [PDF]
Gider V, Budak C.
europepmc +1 more source
Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces
Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley +1 more source
Computational Identification of Potent Multitarget Natural Ligands for Alzheimer's Disease Therapeutics. [PDF]
Sharif N +10 more
europepmc +1 more source
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak +6 more
wiley +1 more source
Receptor interaction profiles of 4-alkoxy-2,6-dimethoxyphenethylamines (Ψ derivatives) and related amphetamines. [PDF]
Kolaczynska KE +4 more
europepmc +1 more source
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang +2 more
wiley +1 more source
Phytochemical, in silico, and in vitro studies of wheatgrass (Triticum aestivum L.) juice powder. [PDF]
Demirag AD +6 more
europepmc +1 more source
Structure–Transport–Ion Retention Coupling for Enhanced Nonvolatile Artificial Synapses
Nitrogen incorporation into the conjugated backbone of donor–acceptor polymers enables efficient charge transfer and deep ion embedding in organic electrochemical synaptic transistors (OESTs). This molecular‐level design enhances non‐volatile synaptic properties, providing a new strategy for developing high‐performance and reliable neuromorphic devices.
Donghwa Lee +5 more
wiley +1 more source
Unique territorial and compartmental organization of chromosomes in the holocentric silkworm. [PDF]
Gil J +12 more
europepmc +1 more source

