Results 51 to 60 of about 35,357 (263)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Genetic diversity as revealed by AFLP fingerprinting and systematic relationships of species in Sesbania (Fabaceae) [PDF]
Taeckholmia, 2006 Genetic diversity has been revealed, using AFLP finger printing, in 37accessions representing 21 species of Sesbania. The AFLP data has beenanalyzed and distance trees, illustrating the relationships within andamong species, have been constructed using ...
Hanaa El-Shazly
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Frontiers in Immunology, 2022 DNA mutagenesis during antibody affinity maturation has potentially oncogenic or autoimmune outcomes if not tightly controlled as it is in mammalian germinal centers.
Doaa Waly +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Applying Hotspot Detection Methods in Forestry: A Case Study of Chestnut Oak Regeneration
International Journal of Forestry Research, 2010 Hotspot detection has been widely adopted in health sciences for disease surveillance, but rarely in natural resource disciplines. In this paper, two spatial scan statistics (SaTScan and ClusterSeer) and a nonspatial classification and regression trees ...
Songlin Fei
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
AncesTree: An interactive immunoglobulin lineage tree visualizer.
PLoS Computational Biology, 2020 High-throughput sequencing of human immunoglobulin genes allows analysis of antibody repertoires and the reconstruction of clonal lineage evolution. The study of antibodies (Abs) affinity maturation is of specific interest to understand the generation of
Mathilde Foglierini +4 more
doaj +1 more source
Random Walks on the Affine Group of a Homogeneous Tree in the Drift-Free Case [PDF]
Journal of Theoretical Probability, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Buraczewski, Dariusz, Kolesko, Konrad
openaire +1 more source
Advanced Engineering Materials, EarlyView.We develop a data‐driven method to derive the mathematical expressions of the Flory–Huggins interaction parameter χ for the swelling behavior of temperature–responsive hydrogels. Starting from initial assumptions of χ, our workflow combines Bayesian optimization, Flory–Rehner theory, and symbolic regression to generate candidate χ expressions.
Yawen Wang +2 more
wiley +1 more source