Results 21 to 30 of about 15,450 (266)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Zanco Journal of Humanity Sciences, 2023 This study discusses the impact of accepting differences, on affirmative action, by Badiu al-Zamam Saeid Nursi. Nursi is one of the icons of the Kurds who devoted their lives to the reunion of the scatters of Umma and restoring its glory. The research
Luqman Bahaaulddin Ahmed
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Affirmative Action for Minorities in India: Constraints and Possibilities
Historia Social y de la Educación, 2016 India is one of the most socially fragmented and unequal societies of the world. At the same time, it has the distinction of having the longest history of most elaborative affirmative action programmes for alleviating socially structured inequalities ...
Mohd. Sanjeer Alam
doaj +1 more source
Affirmative Action in the United States and Positive Action in the EU and Austria – A Comparison
Austrian Law Journal, 2021 Equality is a fundamental principle of democratic society. However, equality in law does not automatically mean equality in opportunity and chances. Insofar, affirmative or positive action measures can be used as a tool to promote broader social mobility
Kapsar, Marina
doaj +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
A commentary on the positive discrimination policy of India [PDF]
Potchefstroom Electronic Law Journal, 2009 Affirmative action and discriminatory measures are complex and controversial issues. The goal of affirmative action is to speed up the creation of a representative and equitable workforce and to assist those who were historically disadvantaged by unfair ...
T Deane
doaj
Affirmative Action: Oppressive In Nature?
Acta Economica et Turistica, 2019 Affirmative action, contrary to the views of many, hurts the very people it was presumably enacted to help: members of minority groups.
Walter E. Block, Alex Hernandez
doaj +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source