Results 31 to 40 of about 4,951 (239)

Multimodal Attention-Based Instruction-Following Part-Level Affordance Grounding

Applied Sciences
The integration of language and vision for object affordance understanding is pivotal for the advancement of embodied agents. Current approaches are often limited by reliance on segregated pre-processing stages for language interpretation and object ...
Wen Qu, Lulu Guo, Jian Cui, Xiao Jin
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Examining Generative AI User Disclosure Intention: A Perceived Affordance Perspective

Journal of Theoretical and Applied Electronic Commerce Research
Generative AI needs to collect user data to provide more accurate answers. This may raise users’ privacy concern and undermine their disclosure intention.
Tao Zhou, Xiaoying Wu
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Affordance [PDF]

Affordance describes an object or space in terms of the actions made possible for the human in the meeting of a design (or non-design) of anything. Affordance is a key concept across all scales of design, as it allows us to not only understand a site, structure, or object in terms of its physical, aesthetical, and material, properties but how these ...
Linda Nhu Laursen, Ole B. Jensen, Markus Löchtefeld   +2 more
  +4 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

ICT-based Learning Personalization Affordance in the Context of Implementation of Constructionist Learning Activities

Informatics in Education, 2015
How to enable students to create a personalized learning environment? What are the criteria of evaluation of the ICT-based learning process personalization affordance?
Natalija IGNATOVA, Valentina DAGIENĖ, Svetlana KUBILINSKIENĖ   +2 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Reduced processing of afforded actions while observing mental content as ongoing mental phenomena

Scientific Reports
While consciousness is typically considered equivalent to mental contents, certain meditation practices—including open monitoring (OM)—are said to enable a unique conscious state where meditators can experience mental content from a de-reified ...
Sucharit Katyal, Oussama Abdoun, Hugues Mounier, Antoine Lutz   +3 more
doaj   +1 more source

Training-Free Affordance Labeling and Exploration Using Subspace Projection and Manifold Curvature Over Pre-Trained Deep Networks

IEEE Access
The advancement in computing power has significantly reduced the training times for deep learning, enabling the rapid development of networks designed for object recognition.
Ismail Ozcil, A. Bugra Koku
doaj   +1 more source