Results 51 to 60 of about 13,508 (304)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Doggone affordances: Canine perception of affordances for reaching [PDF]

open access: yesPsychonomic Bulletin & Review, 2017
Performing any behavior requires perceiving affordances-whether and how that behavior can be performed. Perception of affordances exhibits action scaling-choices about when to transition between two different modes of behavior reflect the fit between action capabilities and environmental properties.
Jeffrey B, Wagman   +2 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Enhancing task-oriented robotic grasping via 3D affordance grounding from vision-language models

open access: yesComplex & Intelligent Systems
Existing task-oriented grasping approaches often rely on 2D pixel-wise affordance segmentation or predefined part annotations, limiting their applicability in unstructured 3D environments and constraining the grasp planning space.
Wenkai Chen   +4 more
doaj   +1 more source

Multimodal Attention-Based Instruction-Following Part-Level Affordance Grounding

open access: yesApplied Sciences
The integration of language and vision for object affordance understanding is pivotal for the advancement of embodied agents. Current approaches are often limited by reliance on segregated pre-processing stages for language interpretation and object ...
Wen Qu, Lulu Guo, Jian Cui, Xiao Jin
doaj   +1 more source

Understanding affordances: history and contemporary development of Gibson’s central concept [PDF]

open access: yesAvant, 2012
Gibson developed the affordance concept to complement his theory of direct perception that stands in sharp contrast with the prevalent inferential theories of perception. A comparison of the two approaches shows that the distinction between them also has
Dobromir G. Dotov   +2 more
doaj  

The Relative Nature of Perception: A Response to Cañal-Bruland and van der Kamp (2015)

open access: yesi-Perception, 2015
Cañal-Bruland and van der Kamp present an argument about the incommensurate relationship between affordance perception and spatial perception in a criticism of Proffitt and Linkenauger’s phenotypic approach to perception.
Sally A. Linkenauger
doaj   +1 more source

Affordance

open access: yes, 2012
1. (n.) An affordance is an action possibility formed by the relationship between an agent and its environment (J. Gibson 1977; J. Gibson 1979). For any combination of agent or environment, any given affordance either exists or does not exist.
Benjamin D. Nye   +3 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

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