Results 31 to 40 of about 5,254 (264)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Enhancing task-oriented robotic grasping via 3D affordance grounding from vision-language models

Complex & Intelligent Systems
Existing task-oriented grasping approaches often rely on 2D pixel-wise affordance segmentation or predefined part annotations, limiting their applicability in unstructured 3D environments and constraining the grasp planning space.
Wenkai Chen, Shang-Ching Liu, Qingdu Li, Yung-Hui Li, Jianwei Zhang   +4 more
doaj   +1 more source

Understanding affordances: history and contemporary development of Gibson’s central concept [PDF]

Avant, 2012
Gibson developed the affordance concept to complement his theory of direct perception that stands in sharp contrast with the prevalent inferential theories of perception. A comparison of the two approaches shows that the distinction between them also has
Dobromir G. Dotov, Lin Nie, Matthieu M. de Wit   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Multimodal Attention-Based Instruction-Following Part-Level Affordance Grounding

Applied Sciences
The integration of language and vision for object affordance understanding is pivotal for the advancement of embodied agents. Current approaches are often limited by reliance on segregated pre-processing stages for language interpretation and object ...
Wen Qu, Lulu Guo, Jian Cui, Xiao Jin
doaj   +1 more source

The Relative Nature of Perception: A Response to Cañal-Bruland and van der Kamp (2015)

i-Perception, 2015
Cañal-Bruland and van der Kamp present an argument about the incommensurate relationship between affordance perception and spatial perception in a criticism of Proffitt and Linkenauger’s phenotypic approach to perception.
Sally A. Linkenauger
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Examining Generative AI User Disclosure Intention: A Perceived Affordance Perspective

Journal of Theoretical and Applied Electronic Commerce Research
Generative AI needs to collect user data to provide more accurate answers. This may raise users’ privacy concern and undermine their disclosure intention.
Tao Zhou, Xiaoying Wu
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

ICT-based Learning Personalization Affordance in the Context of Implementation of Constructionist Learning Activities

Informatics in Education, 2015
How to enable students to create a personalized learning environment? What are the criteria of evaluation of the ICT-based learning process personalization affordance?
Natalija IGNATOVA, Valentina DAGIENĖ, Svetlana KUBILINSKIENĖ   +2 more
doaj   +1 more source