Results 41 to 50 of about 43,338 (305)

Cultural Affordances and Social Media [PDF]

open access: yes, 2021
This paper first reviews the development and application of affordances theory in the field of social media studies. Then, it examines the significance and limitations of the original meaning of affordances of the environment that is provided by American
Yinan Sun   +4 more
core   +1 more source

N300 and social affordances: a study with a real person and a dummy as stimuli. [PDF]

open access: yesPLoS ONE, 2012
Pictures of objects have been shown to automatically activate affordances, that is, actions that could be performed with the object. Similarly, pictures of faces are likely to activate social affordances, that is, interactions that would be possible with
J Bruno Debruille   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Doggone affordances: Canine perception of affordances for reaching [PDF]

open access: yesPsychonomic Bulletin & Review, 2017
Performing any behavior requires perceiving affordances-whether and how that behavior can be performed. Perception of affordances exhibits action scaling-choices about when to transition between two different modes of behavior reflect the fit between action capabilities and environmental properties.
Jeffrey B, Wagman   +2 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

A new paradigm to study social and physical affordances as model-based reinforcement learning

open access: yesCognitive Robotics
Social affordances, although key in human-robot interaction processes, have received little attention in robotics. Hence, it remains unclear whether the prevailing mechanisms to exploit and learn affordances in the absence of human interaction can be ...
Augustin Chartouny   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Feature Analysis: A Method for Analyzing the Role of Ideology in App Design

open access: yesJournal of Digital Social Research, 2021
Many apps are designed to solve a problem or accomplish a task, such as managing a health condition, creating a to-do-list, or finding work. The solutions that app developers offer reflects how they believe that users and other stakeholders understand ...
Amy A. Hasinoff, Rena Bivens
doaj   +1 more source

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