Results 61 to 70 of about 64,207 (291)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Stable and variable affordances are both automatic and flexible

Frontiers in Human Neuroscience, 2015
The mere observation of pictures or words referring to manipulable objects is sufficient to evoke their affordances since objects and their nouns elicit components of appropriate motor programs associated with object interaction. While nobody doubts that
Anna M Borghi, Lucia eRiggio
doaj   +1 more source

Visual and linguistic cues to graspable objects. [PDF]

, 2013
Two experiments investigated (1) how activation of manual affordances is triggered by visual and linguistic cues to manipulable objects and (2) whether graspable object parts play a special role in this process.
Cangelosi, A.; id_orcid, Fischer, Martin H. (Prof. Dr.), Ellis, Rob, Myachykov, Andriy, Fischer, M.H., Myachykov, A., Cangelosi, Angelo, Ellis, R., Fischer, Martin H., Fischer, Martin   +9 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Affordance-Based Human–Robot Interaction With Reinforcement Learning

IEEE Access, 2023
Planning precise manipulation in robotics to perform grasp and release-related operations, while interacting with humans is a challenging problem. Reinforcement learning (RL) has the potential to make robots attain this capability.
Francisco Munguia-Galeano, Satheeshkumar Veeramani, Juan David Hernandez, Qingmeng Wen, Ze Ji   +4 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

A Needs-Affordances-Satisfaction Perspective on the Use of Connected Objects [PDF]

, 2023
Individuals living a digital life find being connected via digital technologies is increasingly important to their overall well-being, especially as more and more everyday life objects provide connectivity features.
Marz, D., Matt, C., Hanelt, A.
core  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Affordances of spreadsheets in mathematical investigation: Potentialities for learning [PDF]

, 2010
This article, is concerned with the ways learning is shaped when mathematics problems are investigated in spreadsheet environments. It considers how the opportunities and constraints the digital media affords influenced the decisions the students made ...
Calder, Nigel Stuart
core