An Updated Review on the Secondary Metabolites and Biological Activities of Aspergillus ruber and Aspergillus flavus and Exploring the Cytotoxic Potential of Their Isolated Compounds Using Virtual Screening. [PDF]
Evid Based Complement Alternat Med, 2021 The secondary metabolites and biological activities of Aspergillus ruber and Aspergillus flavus were comprehensively reported. About 70 compounds were isolated from both species that belong to different classes using conventional and advanced chromatographic techniques and unambiguously elucidated employing one‐ and two‐dimensional nuclear magnetic ...
Youssef FS, Singab ANB.
europepmc +2 more sources
Pericarditis Caused by Enterococcus faecium with Acute Liver Failure Treated by a Multifaceted Approach including Antimicrobials and Hemoadsorption. [PDF]
Case Rep Crit Care, 2021 Background. Sepsis and septic shock are still life‐threatening diseases with a high mortality rate. We report a complex case of peritonitis with pericarditis and acute liver failure caused by septic shock. Potentially hepatotoxic antibiotic therapy levels were monitored using the liver maximum capacity (LiMAx®) test, and standard treatment was ...
Köhler T +7 more
europepmc +2 more sources
Assessment of the feed additive consisting of <i>Bacillus velezensis</i>ATCC PTA-6737 (PB6) for turkeys for fattening and turkeys reared for breeding for the renewal of its authorisation and the modification of the conditions of the authorisation for other growing poultry species (Kemin Europe N.V). [PDF]
EFSA JAbstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on Bacillus velezensis ATCC PTA‐6737 as a zootechnical additive (functional group: gut‐flora stabiliser) in the context of the renewal of the authorisation for turkeys for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +19 more
europepmc +2 more sources
Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology. [PDF]
PLoS ONE, 2012 Mutations in the TP53 gene are the most common alterations in human tumours. TP53 mutational patterns have sometimes been linked to carcinogen exposure.
Vincent Paget +8 more
doaj +2 more sources
Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways. [PDF]
Biomed Res Int, 2014 Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact cause of cancer development and progression is not fully known. But it is thought that cancer occurs due to the structural and functional changes in the genes. The current approach to cancer treatment based on allopathic is expensive, exhibits side effects; and
Rahmani AH +3 more
europepmc +2 more sources
Circulating tumor cells measurements in hepatocellular carcinoma. [PDF]
Int J Hepatol, 2012 Liver cancer is the fifth most common cancer in men and the seventh in women. During the past 20 years, the incidence of HCC has tripled while the 5‐year survival rate has remained below 12%. The presence of circulating tumor cells (CTC) reflects the aggressiveness nature of a tumor.
Chiappini F.
europepmc +2 more sources
Lehren aus dem Gruppieren von Chemikalien zur Bewertung der Risiken für die Gesundheit des Menschen
Angewandte Chemie, Volume 135, Issue 22, May 22, 2023., 2023 Bei der Gruppierung für die Risikobewertung kann die Ähnlichkeit von intrinsischen Eigenschaften (z. B. Struktur), extrinsischen Eigenschaften (z. B. Persistenz) und toxikologischen Eigenschaften (z. B. Genotoxizität) herangezogen werden. Basierend auf den Erfahrungen mit mehreren Stoffklassen leiten wir Grundsätze der Gruppierung ab und differenzieren
Wendel Wohlleben +2 more
wiley +1 more source
Addressing another threat to food safety: Conflict
PLANTS, PEOPLE, PLANET, Volume 5, Issue 3, Page 317-323, May 2023., 2023 The conflict between Ukraine and Russia will negatively affect not only food security but also food safety. Crops produced in Ukraine and Russia are at little risk of contamination by mycotoxins such as aflatoxin. However, due to the conflict, wheat, maize, sunflower, and other crops that would have been produced in and exported from Ukraine will need ...
Alejandro Ortega‐Beltran +1 more
wiley +1 more source
Productive biofilms: from prokaryotic to eukaryotic systems
Journal of Chemical Technology &Biotechnology, Volume 97, Issue 11, Page 3049-3064, November 2022., 2022 Abstract Biofilms have great potential for producing valuable products more efficiently than suspended cultivations when it comes to yield and productivity. In addition, biofilms have the advantage of cell protection and increased resistance to environmental influences.
Andrea Schmeckebier +2 more
wiley +1 more source
Angewandte Chemie, Volume 133, Issue 28, Page 15741-15749, July 5, 2021., 2021 Eine Struktur‐Aktivitäts‐Beziehung des Naturstoffs Leucinostatin A führte zu zwei hochpotenten Verbindungen gegen das Protozoon Trypanosoma brucei mit verminderter toxischer Wirkung in vitro und in vivo. Diese Verbindungen bildeten keine Resistenzen bei langzeitiger subletaler Exposition und ihr Wirkmechanismus liegt in der Destabilisierung der inneren
Michael Brand +14 more
wiley +1 more source