Results 1 to 10 of about 137,799 (265)

Conidium Specific Polysaccharides in Aspergillus fumigatus

Journal of Fungi, 2023
Earlier studies have shown that the outer layers of the conidial and mycelial cell walls of Aspergillus fumigatus are different. In this work, we analyzed the polysaccharidome of the resting conidial cell wall and observed major differences within the ...
Zhonghua Liu, Isabel Valsecchi, Rémy A. Le Meur, Catherine Simenel, J. Iñaki Guijarro, Catherine Comte, Laetitia Muszkieta, Isabelle Mouyna, Bernard Henrissat, Vishukumar Aimanianda, Jean-Paul Latgé, Thierry Fontaine   +11 more
doaj   +1 more source

The New GPI-Anchored Protein, SwgA, Is Involved in Nitrogen Metabolism in the Pathogenic Filamentous Fungus Aspergillus fumigatus

Journal of Fungi, 2023
GPI-anchored proteins display very diverse biological (biochemical and immunological) functions. An in silico analysis has revealed that the genome of Aspergillus fumigatus contains 86 genes coding for putative GPI-anchored proteins (GPI-APs).
Marketa Samalova, Patricia Flamant, Rémi Beau, Mike Bromley, Maryse Moya-Nilges, Thierry Fontaine, Jean-Paul Latgé, Isabelle Mouyna   +7 more
doaj   +1 more source

Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus

mBio, 2021
The compound Congo red (CR) has been historically used for coloring treatment and histological examination as well to inhibit the growth of yeast and filamentous fungi.
Zhonghua Liu, Shriya Raj, Norman van Rhijn, Marcin Fraczek, Jean-Philippe Michel, Odile Sismeiro, Rachel Legendre, Hugo Varet, Thierry Fontaine, Michael Bromley, Jean-Paul Latgé   +10 more
doaj   +1 more source

Invasive pulmonary aspergillosis in critically ill patients with pneumonia due to COVID-19, influenza, and communityacquired pneumonia: A prospective observational study [PDF]

Current Medical Mycology, 2022
Background and Purpose: Influenza A and SARS-CoV-2 are risk factors for invasive pulmonary aspergillosis. Both influenza-associated pulmonary aspergillosis and COVID-19-associated pulmonary aspergillosis result in high mortality and poor clinical ...
Ahsan Syed, Kausar Jabeen, Joveria Farooqi, Hammad Niamatullah, Aisha Fareed Siddiqui, Safia Awan, Alishah Akbar, Irfan Muhammad   +7 more
doaj   +1 more source

Aspergillus fumigatus, One Uninucleate Species with Disparate Offspring

Journal of Fungi, 2021
Establishment of a fungal infection due to Aspergillus fumigatus relies on the efficient germination of the airborne conidia once they penetrate the respiratory tract. However, the features of conidial germination have been poorly explored and understood
François Danion, Norman van Rhijn, Alexandre C. Dufour, Rachel Legendre, Odile Sismeiro, Hugo Varet, Jean-Christophe Olivo-Marin, Isabelle Mouyna, Georgios Chamilos, Michael Bromley, Anne Beauvais, Jean-Paul Latgé   +11 more
doaj   +1 more source

Volatile Compounds Emitted by Pseudomonas aeruginosa Stimulate Growth of the Fungal Pathogen Aspergillus fumigatus

mBio, 2016
Chronic lung infections with opportunistic bacterial and fungal pathogens are a major cause of morbidity and mortality especially in patients with cystic fibrosis.
Benoit Briard, Christoph Heddergott, Jean-Paul Latgé   +2 more
doaj   +1 more source

Two KTR Mannosyltransferases Are Responsible for the Biosynthesis of Cell Wall Mannans and Control Polarized Growth in Aspergillus fumigatus

mBio, 2019
Fungal cell wall mannans are complex carbohydrate polysaccharides with different structures in yeasts and molds. In contrast to yeasts, their biosynthetic pathway has been poorly investigated in filamentous fungi.
Christine Henry, Jizhou Li, François Danion, Laura Alcazar-Fuoli, Emilia Mellado, Rémi Beau, Grégory Jouvion, Jean-Paul Latgé, Thierry Fontaine   +8 more
doaj   +1 more source

The Dual Activity Responsible for the Elongation and Branching of β-(1,3)-Glucan in the Fungal Cell Wall

mBio, 2017
β-(1,3)-Glucan, the major fungal cell wall component, ramifies through β-(1,6)-glycosidic linkages, which facilitates its binding with other cell wall components contributing to proper cell wall assembly.
Vishukumar Aimanianda, Catherine Simenel, Cecile Garnaud, Cecile Clavaud, Rui Tada, Lise Barbin, Isabelle Mouyna, Christoph Heddergott, Laura Popolo, Yoshikazu Ohya, Muriel Delepierre, Jean-Paul Latge   +11 more
doaj   +1 more source

Members of Glycosyl-Hydrolase Family 17 of A. fumigatus Differentially Affect Morphogenesis

Journal of Fungi, 2018
Cell wall biosynthesis and remodeling are essential for fungal growth and development. In the fungal pathogen Aspergillus fumigatus, the β(1,3)glucan is the major cell wall polysaccharide.
Nicolas Millet, Jean-Paul Latgé, Isabelle Mouyna   +2 more
doaj   +1 more source

Interactions between Aspergillus fumigatus and Pulmonary Bacteria: Current State of the Field, New Data, and Future Perspective

Journal of Fungi, 2019
Aspergillus fumigatus and Pseudomonas aeruginosa are central fungal and bacterial members of the pulmonary microbiota. The interactions between A. fumigatus and P. aeruginosa have only just begun to be explored.
Benoit Briard, Gaëtan L. A. Mislin, Jean-Paul Latgé, Anne Beauvais   +3 more
doaj   +1 more source