Results 91 to 100 of about 20,576 (195)

Two-year outcome of an observe-and-plan regimen for neovascular age-related macular degeneration treated with Aflibercept. [PDF]

, 2017
The purpose of our study was to investigate the two-year outcome of Aflibercept treatment for neovascular age-related macular degeneration (nAMD), using the Observe-and-Plan regimen, an individually planned treatment regimen, based on the predictability ...
Ambresin, A., Dirani, A., Mantel, I., Parvin, P., Zola, M.   +4 more
core   +1 more source

Regorafenib as a single-agent in the treatment of patients with gastrointestinal tumors: an overview for pharmacists [PDF]

, 2014
Regorafenib (BAY 73-4506, Stivarga® Bayer HealthCare Pharmaceutical Inc) is an oral multikinase inhibitor with a distinct and wide-ranging profile of tyrosine kinase inhibition, resulting in antiangiogenic and antiproliferative properties in tumors ...
Christophe Tournigand, Jean-Baptiste Rey, Vincent Launay-Vacher   +2 more
core   +1 more source

Intravitreal aflibercept injection in Indian eyes with retinopathy of prematurity

Indian Journal of Ophthalmology, 2019
Purpose: To study the efficacy of intravitreal Aflibercept, an anti Vascular Endothelial Growth factor, (anti-VEGF) in Retinopathy of Prematurity (ROP).
Vasumathy Vedantham
doaj   +1 more source

Biology of advanced uveal melanoma and next steps for clinical therapeutics [PDF]

, 2014
Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes.
Bastian, BC, Bowcock, AM, Carvajal, RD, Flaherty, KT, Gershenwald, JE, Gutkind, JS, Luke, JJ, McKenna, KC, Patel, PM, Sato, T, Selig, S, Sossman, JA, Streicher, HZ, Sznol, M, Thurin, M, Triozzi, PL, Van Meir, EG, Welch, J   +17 more
core   +1 more source

EFFICACY OF INTRAVITREAL AFLIBERCEPT IN MACULAR TELANGIECTASIA TYPE 1 IS LINKED TO THE OCULAR ANGIOGENIC PROFILE. [PDF]

, 2017
To evaluate intravitreal aflibercept in macular telangiectasia Type 1 (MacTel 1) patients and measure their ocular angiogenic profile. Eight subjects with MacTel 1 refractory to bevacizumab, ranibizumab, or laser therapy and switched to aflibercept were ...
Autiero, Brown, Cahill, Cai, Cao, Charbel Issa, Charbel Issa, Christoforidis, Ciarnella, Daruich, Do, Fan, Ferrara, Fischer, Fischer, Gaillard, Gamulescu, Gass, Gass, He, Heier, Kase, Kearney, Kinge, Koay, Kovach, Kowalczuk, Krohne, Kupitz, Loutfi, Matet, Matsumoto, Miyamoto, Moisseiev, Moon, Muether, Noma, Noma, Odorisio, Okamoto, Papadopoulos, Priglinger, Rahimy, Roller, Rouvas, Shibeeb, Shibuya, Sigler, Smithen, Stewart, Takayama, Weickhardt, Witmer, Wolanska, Yannuzzi, Yonekura, Zhang   +56 more
core   +2 more sources

One-Month Real-World Comparison of Aflibercept 8 mg Versus 2 mg in Treatment-Naïve and Previously Treated Eyes with Neovascular Age-Related Macular Degeneration

Biologics
Background/Objectives: The relative efficacy of 8 mg aflibercept compared to 2 mg in treating neovascular age-related macular degeneration (nAMD) has not been fully established. This study aims to compare the visual and anatomical outcomes of aflibercept
Takahiro Mizukami, Satoru Ueno, Soichiro Mishima, Yoshikazu Shimomura   +3 more
doaj   +1 more source

Pharmacoeconomic analysis of anti-angiogenic therapy for diabetic macular edema

Качественная клиническая практика, 2019
Te purpose of the study is to assess the economic consequences of the use of various anti-VEGF drugs in patients with diabetic macular edema (DME).Materials and methods.
S. V. Nedogoda, I. N. Barykina, A. S. Salasyuk, V. O. Smirnova, E. A. Popova   +4 more
doaj   +1 more source

Pre-treatment clinical features in central retinal vein occlusion that predict visual outcome following intravitreal ranibizumab [PDF]

, 2018
Background: Predicting how patients with central retinal vein occlusion (CRVO) will respond to intravitreal anti-VEGF is challenging. The purpose of this study was to identify pre-treatment clinical features in CRVO that predict visual acuity (VA ...
Brogan, Kerr, Gilmour, David Francis, Precup, Monica, Rodger, Amanda, Young, David   +4 more
core   +1 more source

Osteonecrosis of the Jaw Associated with Antiangiogenics in Antiresorptive-Naive Patient: A Comprehensive Review of the Literature [PDF]

, 2018
Objectives. To review the available literature on medication-related osteonecrosis of the jaw (MRONJ) associated with antiangiogenics in antiresorptive-naïve individuals. Methods.
Fedele, S, Pimolbutr, K, Porter, S
core  

Plain language summary of publication of the 48-week results from the PULSAR study investigating how well a new dose of aflibercept works and how safe it is for people with wet age-related macular degeneration

Therapeutic Advances in Ophthalmology
What is this summary about? • This is a summary of a publication about the PULSAR study, which was published in The Lancet scientific journal. • Wet age-related macular degeneration (or AMD) is a long-term eye disease in which abnormal blood vessels grow
Paolo Lanzetta, Jean-François Korobelnik, Jeffrey S. Heier, Sergio Leal, Frank G. Holz, William Lloyd Clark, David Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J. Berliner, Andrea Schulze, Thomas Schmelter, Ursula Schmidt-Ott, Xin Zhang, Robert Vitti, Karen W. Chu, Kimberly Reed, Rohini Rao, Rafia Bhore, Yenchieh Cheng, Tien Y. Wong   +20 more
doaj   +1 more source