Results 1 to 10 of about 17,498 (157)

Pipeline therapies for neovascular age related macular degeneration [PDF]

International Journal of Retina and Vitreous, 2021
Age related macular degeneration (AMD) is the most common cause of vision loss in the elderly population. Neovascular AMD comprises 10% of all cases and can lead to devastating visual loss due to choroidal neovascularization (CNV).
Sruthi Arepalli, Peter K. Kaiser
doaj   +3 more sources

The prechoroidal cleft in neovascular age-related macular degeneration. [PDF]

Acta Ophthalmol
Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular ...
Brouwer NJ, Vu THK, De Jong-Hesse Y, van Dijk EHC.   +3 more
europepmc   +4 more sources

Neovascular age-related macular degeneration without drusen. [PDF]

Acta Ophthalmol
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three ...
Sirks MJ, van Dijk EHC, Ghalayini H, Bazdar S, Yu W, Yzer S, Martinez Ciriano JP, Schlingemann RO, Diederen RMH, Boon CJF.   +9 more
europepmc   +4 more sources

Association of neovascular age-related macular degeneration with migraine [PDF]

Scientific Reports, 2022
Patients with early onset vascular pathology have been reported to manifest neovascular age-related macular degeneration (AMD). While the blood vessels involved in pathogenesis of migraine remains controversial, it is generally accepted that a major ...
Tung-Mei Kuang, Sudha Xirasagar, Yi-Wei Kao, Jau-Der Ho, Herng-Ching Lin   +4 more
doaj   +4 more sources

Neovascular age-related macular degeneration management – Beyond anti-VEGF [PDF]

Indian Journal of Ophthalmology
Intravitreal anti-vascular endothelial growth factor (VEGF) therapy has transformed neovascular age-related macular degeneration (nAMD) into a chronic, treatable condition.
Apoorva Ayachit, Shailesh Rao, Shadma Eqbal, Giriraj Vibhute, Farhat Fatima, Shrinivas Joshi, Guruprasad Ayachit, Jay Chhablani   +7 more
doaj   +2 more sources

Quality of life in patients with neovascular age-related macular degeneration before and after intravitreal therapy: a longitudinal observational study [PDF]

Frontiers in Medicine
BackgroundAge-related macular degeneration is a chronic and progressive disease that typically develops after the age of 50. Characterized by visual distortions, image blurring, and gradual central vision loss, age-related macular degeneration ...
Marta Nowak, Anna Maria Cybulska, Aleksandra Derezińska, Elżbieta Grochans, Mariusz Panczyk, Katarzyna Kęcka, Kamila Rachubińska   +6 more
doaj   +2 more sources

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration [PDF]

New England Journal of Medicine, 2011
Clinical trials have established the efficacy of ranibizumab for the treatment of neovascular age-related macular degeneration (AMD). In addition, bevacizumab is used off-label to treat AMD, despite the absence of similar supporting data.In a multicenter, single-blind, noninferiority trial, we randomly assigned 1208 patients with neovascular AMD to ...
Daniel F Martin, Maureen G Maguire, Gui-Shuang Ying   +2 more
exaly   +3 more sources

Radiotherapy for neovascular age-related macular degeneration [PDF]

Cochrane Database of Systematic Reviews, 2004
Radiotherapy has been proposed as a treatment to prevent new vessel growth in people with neovascular age-related macular degeneration (AMD).The aim of this review was to examine the effects of radiotherapy on neovascular AMD.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Group ...
Sivagnanavel, V, Evans, JR, Ockrim, Z, Chong, V   +3 more
openaire   +6 more sources

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

Health Technology Assessment, 2022
Background: Neovascular age-related macular degeneration is a leading cause of sight loss, and early detection and treatment is important. For patients with neovascular age-related macular degeneration in one eye, it is usual practice to monitor the ...
Katie Banister, Jonathan A Cook, Graham Scotland, Augusto Azuara-Blanco, Beatriz Goulão, Heinrich Heimann, Rodolfo Hernández, Ruth Hogg, Charlotte Kennedy, Sobha Sivaprasad, Craig Ramsay, Usha Chakravarthy   +11 more
doaj   +1 more source

Pegaptanib for neovascular age-related macular degeneration [PDF]

American Journal of Ophthalmology, 2004
Pegaptanib, an anti-vascular endothelial growth factor therapy, was evaluated in the treatment of neovascular age-related macular degeneration.We conducted two concurrent, prospective, randomized, double-blind, multicenter, dose-ranging, controlled clinical trials using broad entry criteria.
Gragoudas, E.S., Adamis, A.P., Cunningham, E.T., Feinsod, M., Guyer, D.R., Study group members AMC, :, Schlingemann, R.O.   +6 more
openaire   +3 more sources