Results 31 to 40 of about 22,288 (223)

Ranibizumab in neovascular age-related macular degeneration

Clinical Interventions in Aging, 2006
Neovascular age-related macular degeneration (AMD) is a visually devastating condition resulting from choroidal neovascularization and secondary photoreceptor loss. Ranibizumab and bevacizumab are medications that target vascular endothelial growth factor (VEGF).
T Eng, Kenneth, Peter J, Kertes
openaire   +2 more sources

Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration - the potential sources and molecular cues for their recruitment and activation

EBioMedicine, 2018
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in developed countries. Neovascular AMD (nAMD) accounts for 90% of AMD-related vision loss.
Karis Little, Jacey H. Ma, Nan Yang, Mei Chen, Heping Xu   +4 more
doaj   +1 more source

Aflibercept for neovascular age-related macular degeneration

Cochrane Database of Systematic Reviews, 2016
Central vision loss caused by age-related macular degeneration (AMD) is the leading cause of blindness among the elderly in developed countries. Neovascular AMD is characterized by choroidal neovascularization (CNV). Growth of new blood vessels in patients with neovascular AMD is driven by a complex process that involves a signal protein called ...
Salman, Sarwar, Elizabeth, Clearfield, Mohamed Kamel, Soliman, Mohammad Ali, Sadiq, Andrew J, Baldwin, Mostafa, Hanout, Aniruddha, Agarwal, Yasir J, Sepah, Diana V, Do, Quan Dong, Nguyen   +9 more
openaire   +3 more sources

Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration

, 2009
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ, Uppal, GS, Rubin, GS, Chen, FK, Tufail, A, Maclaren, Robert, Franzco, FKC, Aylward, GW, Da Cruz, L, MacLaren, RE   +9 more
core   +1 more source

New Therapies of Neovascular AMD beyond Anti-VEGF Injections

Vision, 2018
Neovascular age-related macular degeneration is a leading cause of vision loss among the aging population. The current standard of care to treat neovascular age-related macular degeneration is inhibiting vascular endothelial growth factor (VEGF) through ...
Greggory M. Gahn, Arshad M. Khanani
doaj   +1 more source

Unusual visual loss in a patient with exudative macular degeneration

American Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of marked vision loss in a patient with neovascular age-related macular degeneration after choroidal neovascular membrane (CNV) improvement and stabilization.
Enoch T. Peng, Sean D. Adrean
doaj   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

An Ecological Correlation Study of Late Age-Related Macular Degeneration and the Complement Factor H Y402H Polymorphism

, 2009
PURPOSE: To investigate whether variation in the distribution of the risk allele frequency of the Y402H single-nucleotide polymorphism (SNP) across various ethnicities and geographic regions reflects differences in the prevalence of late age-related ...
Whittaker, John C, Sofat, Reecha, Smeeth, Liam, Nonyane, Bareng A.S., Chakravarthy, Usha, Fletcher, Astrid E., Whittaker, John C., Fletcher, Astrid E, Nitsch, Dorothea, Nonyane, Bareng AS   +9 more
core   +1 more source

Evaluation of Flowmetry Indicators in Patients with a Wet AMD Form during Antiangiogenic Therapy

Oftalʹmologiâ, 2019
Purpose: to assess the effect of aflibercept (Eylea; “Regeneron”, USA) intravitreal injections on ocular blood flow and intraocular pressure parameters in patients with neovascular form of age-related macular degeneration (wet AMD).
N. Yu. Yousef, E. E. Kazaryan, D. M. Safonova, N. Yu. Shkolyarenko, F. B. Dudieva, T. V. Sharnina   +5 more
doaj   +1 more source

Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration

Biomedicines, 2023
Quantitative autofluorescence (qAF8) level is a presumed surrogate marker of lipofuscin content in the retina. We investigated the changes in the qAF8 levels in non-neovascular AMD. In this prospective cohort study, Caucasians aged ≥50 years with varying
Shruti Chandra, Manjot K. Grewal, Sarega Gurudas, Rajan Sondh, Alan Bird, Glen Jeffery, Victor Chong, Sobha Sivaprasad   +7 more
doaj   +1 more source