Results 41 to 50 of about 17,683 (178)

Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration

Biomedicines, 2023
Quantitative autofluorescence (qAF8) level is a presumed surrogate marker of lipofuscin content in the retina. We investigated the changes in the qAF8 levels in non-neovascular AMD. In this prospective cohort study, Caucasians aged ≥50 years with varying
Shruti Chandra, Manjot K. Grewal, Sarega Gurudas, Rajan Sondh, Alan Bird, Glen Jeffery, Victor Chong, Sobha Sivaprasad   +7 more
doaj   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

A Review of Artificial Intelligence in Ophthalmology: Key Aspects, Challenges, and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly reshaping ophthalmology because the specialty depends heavily on structured imaging, quantitative measurements, and repeatable diagnostic workflows. This review provides a clinically grounded and translationally oriented synthesis of AI in ophthalmology, covering methodological foundations ...
Partha Pratim Ray
wiley   +1 more source

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration

Ophthalmology and Therapy
Introduction Neovascular age-related macular degeneration is a global public-health concern, associated with a considerable burden to individuals, healthcare systems, and society.
Anat Loewenstein, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Chui Ming Gemmy Cheung, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Adrian Koh, Jean-François Korobelnik, Xiaofeng Lin, Paul Mitchell, Moira Murphy, Mali Okada, Ian Pearce, Francisco J. Rodriguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Focke Ziemssen, Jane Barratt   +22 more
doaj   +1 more source

Uncomplicated Cataract Surgery and Neovascular Conversion of Age-Related Macular Degeneration: Fifteen-Year Follow-Up Study

Journal of Current Ophthalmology
Purpose: To evaluate the impact of cataract surgery on neovascular age-related macular degeneration (nAMD) conversion over a 15-year follow-up period. Methods: This 15-year retrospective study on dry AMD patients compared Group A (cataract surgery) and ...
Komal Agarwal, Elham Sadeghi, Kunaal Mehrotra, Sandeep Chandra Bollepalli, Kiran Kumar Vupparaboina, Jay Chhablani   +5 more
doaj   +1 more source

Intravitreal conbercept injection for neovascular age-related macular degeneration [PDF]

International Journal of Ophthalmology, 2019
AIM: To evaluate the efficacy and safety of intravitreal injection of conbercept in patients with neovascular age-related macular degeneration (AMD). METHODS: Retrospective review of 66 eyes of 63 patients with neovascular AMD. All patients received 0.5
Bing-Hui Wu, Bing Wang, Hui-Qin Wu, Qin Chang, Hui-Qin Lu   +4 more
doaj   +1 more source

Hypertensive Disorders of Pregnancy and the Long‐Term Risk of Maternal Retinal and Ophthalmic Disease: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are associated with increased long‐term risk of maternal cardio‐metabolic disease, but links with future retinal diseases remain unclear. Objective The objective of this study is to synthesise the published literature on HDP and subsequent retinal and other ophthalmic disease.
Peter Barrett, Cian Carey, Sinéad O'Riordan, Angela Ding Wu, Emma Wallace, Matilda Biba, Karolina Kublickiene, Fergus McCarthy, Ali Khashan   +8 more
wiley   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Exploring market dynamics of biological including biosimilar treatments for retinal diseases in Europe: An interrupted time‐series analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the impact of biosimilar ranibizumab and on‐patent faricimab market entry on pricing and utilization trends and describe national variation in off‐label bevacizumab use in Europe. Methods Interrupted time series analysis of quarterly sales data (Q1 2018–Q2 2024) in 11 European countries evaluated ranibizumab utilization and ...
Elif Car, Isabelle Huys, Steven Simoens, Arnold G. Vulto   +3 more
wiley   +1 more source

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration [PDF]

New England Journal of Medicine, 2011
Clinical trials have established the efficacy of ranibizumab for the treatment of neovascular age-related macular degeneration (AMD). In addition, bevacizumab is used off-label to treat AMD, despite the absence of similar supporting data.In a multicenter, single-blind, noninferiority trial, we randomly assigned 1208 patients with neovascular AMD to ...
Daniel F, Martin, Maureen G, Maguire, Gui-shuang, Ying, Juan E, Grunwald, Stuart L, Fine, Glenn J, Jaffe   +5 more
openaire   +2 more sources