Results 61 to 70 of about 22,288 (223)

Impact of delayed appointments on treatment outcomes in neovascular macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the real‐world visual outcomes of anti‐vascular endothelial growth factor (anti‐VEGF) therapy, the frequency of delayed appointments and the relationship between delays and visual outcomes in patients with neovascular age‐related macular degeneration (nAMD).
Petri Purola, Pekko Hujanen, Hannu Uusitalo, Hannele Uusitalo‐Järvinen   +3 more
wiley   +1 more source

Comparison of the efficacy and safety of SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration

Scientific Reports
To compare the efficacy and safety of the proposed aflibercept biosimilar SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration, this randomized, double-masked, parallel-group, multicenter study was conducted in ...
Se Woong Kang, Jaehwan Choi, Veeral S. Sheth, Agnieszka Nowosielska, Marta Misiuk-Hojlo, András Papp, David M. Brown, Jae-Ho Lee, Yoreh Barak   +8 more
doaj   +1 more source

Deep Learning in Neovascular Age-Related Macular Degeneration

Medicina
Background and objectives: Age-related macular degeneration (AMD) is a complex and multifactorial condition that can lead to permanent vision loss once it progresses to the neovascular exudative stage.
Enrico Borrelli, Sonia Serafino, Federico Ricardi, Andrea Coletto, Giovanni Neri, Chiara Olivieri, Lorena Ulla, Claudio Foti, Paola Marolo, Mario Damiano Toro, Francesco Bandello, Michele Reibaldi   +11 more
doaj   +1 more source

Rhizobium radiobacter Endophthalmitis following Intravitreal Ranibizumab Injection

Case Reports in Ophthalmology, 2012
We present the first reported case of acute endophthalmitis due to Rhizobium radiobacter after an intravitreal injection of ranibizumab for neovascular age-related macular degeneration.
Lavnish Joshi, Jiten Morarji, Oren Tomkins-Netzer, Sue Lightman, Simon R.J. Taylor   +4 more
doaj   +1 more source

Aqueous Humour Cytokines as Predictors of Axial Elongation in High Myopia: A 2‐Year Longitudinal Cohort Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate the predictive value of aqueous humour cytokines for axial elongation. Methods This was a prospective longitudinal observational study. 72 high myopia patients (72 eyes) who received implantable collamer lens (ICL) implantation surgery with at least 2 years of follow‐up were included.
Lihui Meng, Yan Luo, Zhengming Shi, Youxin Chen, Zhikun Yang   +4 more
wiley   +1 more source

Gene Therapies for Neovascular Age-Related Macular Degeneration [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
Pathological neovascularization is a key component of the neovascular form (also known as the wet form) of age-related macular degeneration (AMD) and proliferative diabetic retinopathy. Several preclinical studies have shown that antiangiogenesis strategies are effective for treating neovascular AMD in animal models. Vascular endothelial growth factor (
Peter, Pechan, Samuel, Wadsworth, Abraham, Scaria   +2 more
openaire   +2 more sources

Risk of Age‐Related Ocular Diseases in Non‐Diabetic Adults With Obesity Using Glucagon‐Like Peptide 1 Receptor Agonists

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess whether glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are associated with a lower incidence of age‐related ocular diseases in non‐diabetic older adults with overweight or obesity. Materials and Methods We conducted a retrospective, propensity score–matched cohort study using the TriNetX global research network.
Kuo‐En Chen, Po‐Chun Wang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Spotlight on Faricimab in the Treatment of Wet Age-Related Macular Degeneration: Design, Development and Place in Therapy

Drug Design, Development and Therapy, 2022
Archana A Nair, Avni P Finn, Paul Sternberg Jr Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USACorrespondence: Paul Sternberg Jr, Chair and G. W.
Nair AA, Finn AP, Sternberg P Jr
doaj  

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source