Results 61 to 70 of about 31,199 (226)

A variance components factor model for genetic association studies: a Bayesian analysis.

, 2010
Studies of gene-trait associations for complex diseases often involve multiple traits that may vary by genotype groups or patterns. Such traits are usually manifestations of lower-dimensional latent factors or disease syndromes.
Nonyane, BAS, Whittaker, JC
core   +1 more source

Refinement and preliminary evaluation of two tablet-based tests of real-world visual function [PDF]

, 2019
PURPOSE: To describe, refine, evaluate, and provide normative control data for two freely available tablet-based tests of real-world visual function, using a cohort of young, normally-sighted adults.
Bi, W., Crabb, D. P., Demaria, G., Jones, P. R., Taylor, D. J., Tigchelaar, I., Wilson, I.   +6 more
core   +2 more sources

Association of treated neovascular AMD with disability and mood disorders: A longitudinal nationwide study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the associations of treated neovascular AMD with the risk of disability, falls, fractures and mood disorders in a large sample representative of the French population. Methods Analyses were based on 77 582 individuals belonging to the ‘Echantillon Généraliste des Bénéficiaires’, a 1/97 random sample of the French population,
Cécile Delcourt, Emilie Hucteau, Sarra Gattoussi, Karine Pérès, Marie‐Noelle Delyfer, Catherine Helmer, Jean‐François Korobelnik   +6 more
wiley   +1 more source

Strategies for improving early detection and diagnosis of neovascular age-related macular degeneration [PDF]

, 2015
Treatment of the neovascular form of age-related macular degeneration (AMD) has been revolutionized by the introduction of such agents as ranibizumab, bevacizumab, and aflibercept.
Agrawal, Rupesh, De Salvo, Gabriella, Goverdhan, Srini, Keane, Pearse A., Sim, Dawn A., Tufail, Adnan   +5 more
core   +2 more sources

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

The effect of intravitreal administration of bevacizumab on macular edema and visual acuity in age-related macular degeneration with subfoveolar choroidal neovascularisation [PDF]

, 2013
Background/Aim. Age-related macular degeneration (AMD) is a leading cause of the loss of central visual acuity in population older than 70 years. We can distinguish wet and dry form of AMD.
Cerović Vesna, Draganić Biljana, Janićijević-Petrović Mirjana, Petrović Nenad, Ristić Dragana, Vukosavljević Miroslav   +5 more
core   +1 more source

Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies, Yohei Hashimoto, Rahman Nazari, Jennifer Arnold, Beibei Wang, Richard Barry, Ross Ferrier, Justin Game, Daniel Barthelmes   +8 more
wiley   +1 more source

Comparison of the efficacy and safety of SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration

Scientific Reports
To compare the efficacy and safety of the proposed aflibercept biosimilar SCD411 and reference aflibercept in patients with neovascular age-related macular degeneration, this randomized, double-masked, parallel-group, multicenter study was conducted in ...
Se Woong Kang, Jaehwan Choi, Veeral S. Sheth, Agnieszka Nowosielska, Marta Misiuk-Hojlo, András Papp, David M. Brown, Jae-Ho Lee, Yoreh Barak   +8 more
doaj   +1 more source

Prognostic Factors in Patients With Submacular Haemorrhage Complicating Age‐Related Macular Degeneration: A Post Hoc Analysis of the STAR Study

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate prognostic factors of recent submacular haemorrhage (SMH) complicating neovascular age‐related macular degeneration (nAMD) treated with surgery or pneumatic displacement combined with intravitreal injection of anti‐vascular endothelial growth factor.
Pierre‐Henry Gabrielle, Petra Eid, Ludwig Serge Aho, Laurent Kodjikian, Eric Souied, Joel Uzzan, Jean Baptiste Conart, Marie‐Noëlle Delyfer, Catherine Creuzot‐Garcher   +8 more
wiley   +1 more source

Deep Learning in Neovascular Age-Related Macular Degeneration

Medicina
Background and objectives: Age-related macular degeneration (AMD) is a complex and multifactorial condition that can lead to permanent vision loss once it progresses to the neovascular exudative stage.
Enrico Borrelli, Sonia Serafino, Federico Ricardi, Andrea Coletto, Giovanni Neri, Chiara Olivieri, Lorena Ulla, Claudio Foti, Paola Marolo, Mario Damiano Toro, Francesco Bandello, Michele Reibaldi   +11 more
doaj   +1 more source