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Physical activity and the risk of cataract and age-related macular degeneration: a systematic review and meta-analysis of cohort studies [PDF]
BMC OphthalmologyBackground Physical activity has been associated with a lower risk of cataract and age-related macular degeneration in some studies; however, the available evidence has not been fully consistent.
Dagfinn Aune +5 more
doaj +2 more sources
Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
Frontiers in Neurology, 2022 Our aim was to determine whether the genetic liability to sleep and pain-related traits have a causal effect on risk of neurodegeneration in individuals of predominantly European ancestry. We selected five neurodegenerative disorders, namely, age-related
Sandeep Grover +2 more
doaj +1 more source
Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
, 2012 The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Birke, Kerstin +3 more
core +10 more sources
Innate immune biology in age-related macular degeneration
Frontiers in Cell and Developmental Biology, 2023 Age-related macular degeneration (AMD) is a neurodegenerative disease and a leading cause of irreversible vision loss in the developed world. While not classically described as an inflammatory disease, a growing body of evidence has implicated several ...
Karina Ascunce +4 more
doaj +1 more source
PLoS ONE, 2021 ObjectiveThis study aimed to investigate the risk of Alzheimer's disease among patients with age-related macular degeneration and its association with confounding comorbidities.MethodThis was a population-based, retrospective cohort study.
Li-Yen Wen +9 more
doaj +1 more source
Classification of dry and wet macular degeneration based on the ConvNeXT model
Frontiers in Computational Neuroscience, 2022 PurposeTo assess the value of an automated classification model for dry and wet macular degeneration based on the ConvNeXT model.MethodsA total of 672 fundus images of normal, dry, and wet macular degeneration were collected from the Affiliated Eye ...
Maonian Wu +11 more
doaj +1 more source
Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction
Molecular Therapy: Methods & Clinical Development, 2020 The intravitreal (IVT) injection method is a choice when targeting the inner retina for gene therapy. However, the transduction efficiency of adeno-associated virus (AAV) vectors administered by the IVT route is usually low and may be affected by several
Sanjar Batirovich Madrakhimov +5 more
doaj +1 more source
Age Related Macular Degeneration and Total Hip Replacement Due to Osteoarthritis or Fracture: Melbourne Collaborative Cohort Study. [PDF]
PLoS ONE, 2015 Osteoarthritis is the leading cause of total hip replacement, accounting for more than 80% of all total hip replacements. Emerging evidence suggests that osteoarthritis has a chronic inflammatory component to its pathogenesis similar to age-related ...
Elaine W Chong +8 more
doaj +1 more source
PLoS ONE, 2023 BackgroundAge-related macular degeneration is the primary cause of irreversible blindness in developed countries, whereas the global prevalence of osteoporosis-a major public health problem-is 19.7%.
Agnieszka Budnik +9 more
doaj +1 more source
Juvenile Macular Degenerations [PDF]
Seminars in Pediatric Neurology, 2017 In this article, we review the following 3 common juvenile macular degenerations: Stargardt disease, X-linked retinoschisis, and Best vitelliform macular dystrophy. These are inherited disorders that typically present during childhood, when vision is still developing.
Altschwager P. +4 more
openaire +4 more sources