Results 11 to 20 of about 285,624 (259)

Age-related macular degeneration

Community Eye Health Journal, 2014
Age-related macular degeneration (AMD) is a disease of the retina that usually develops in people aged 60 years and older. It affects about 8.7% of the world’s population and is the leading cause of blindness among people aged 50 and older in ...
Wanjiku Mathenge
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Age-related macular degeneration

Clinical Ophthalmology, 2011
Giuseppe Querques¹, Fernando Onofrio Avellis1,2, Lea Querques1,3, Francesco Bandello³, Eric H Souied¹ ¹Service d'Ophtalmologie, Centre Hospitalier Intercommunal Créteil, Université Paris ...
Querques G, Avellis FO, Querques L, Bandello F, Souied EH   +4 more
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Modelling the Genetic Risk in Age-Related Macular Degeneration [PDF]

, 2012
Late-stage age-related macular degeneration (AMD) is a common sight-threatening disease of the central retina affecting approximately 1 in 30 Caucasians.
Weber, Bernhard H. F., Lars G. Fritsche, Weber, Bernhard H.F., Bernhard H. F. Weber, Grassmann, F., Iris M Heid, Grassmann, Felix, Lars G Fritsche, Fritsche Lars G., Keilhauer Claudia N., Keilhauer, Claudia N., Claudia N. Keilhauer, Claudia N. Keilhauer (162279), Heid, I.M., Heid, Iris M., Felix Grassmann, Felix Grassmann (162264), Fritsche, Lars G., Keilhauer, C.N., Claudia N Keilhauer, Iris M. Heid, Weber, B.H.F., Bernhard H F Weber, Grassmann Felix, Lars G. Fritsche (162272), Fritsche, L.G., Bernhard H. F. Weber (162289), Heid Iris M., Weber Bernhard H. F., Iris M. Heid (87553)   +29 more
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Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration [PDF]

, 2009
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ, Uppal, GS, Rubin, GS, Chen, FK, Tufail, A, Maclaren, Robert, Franzco, FKC, Aylward, GW, Da Cruz, L, MacLaren, RE   +9 more
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Candidate gene study of macular response to supplemental lutein and zeaxanthin. [PDF]

, 2013
Supplementation with carotenoids is proposed to protect against age-related macular degeneration. There is, however, considerable variability in retinal macular pigment response, which may be due to underlying genetic variation. The purpose of this study
Liew, SH Melissa, Venturini, Cristina, Williams, Katherine; id_orcid, Beatty, Stephen, Hysi, Pirro G., Williams, Katie M., Gilbert, Clare E, Gilbert, Clare E., Hysi, Pirro G, Williams, Katie M, Nag, Abhishek, Hammond, Christopher J., Liew, S.H. Melissa, Yonova-Doing, Ekaterina, Hammond, Christopher J, Liew, S H Melissa   +15 more
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mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV

Cell Communication and Signaling, 2019
Background The mechanistic target of rapamycin (mTOR) pathway is a potential target to inhibit pathologic processes in choroidal neovascularization. However, the exact role of mTOR signaling in the development of CNV remains obscure.
Jin Young Yang, Sanjar Batirovich Madrakhimov, Dong Hyuck Ahn, Hun Soo Chang, Sang Joon Jung, Seung Kwan Nah, Ha Yan Park, Tae Kwann Park   +7 more
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The estimated prevalence and incidence of late stage age related macular degeneration in the UK [PDF]

, 2012
BACKGROUND: UK estimates of age related macular degeneration (AMD) occurrence vary. AIMS: To estimate prevalence, number and incidence of AMD by type in the UK population aged ≥50 years.
Fletcher, AE, Owen, CG, Rudnicka, AR, Fletcher, Astrid E, Rudnicka, Alicja R, Jarrar, Z, Cook, DG, Wormald, Richard, Wormald, R, Owen, Christopher G, Jarrar, Zakariya, Cook, Derek G   +11 more
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Dual Sensory Impairment: The Correlation between Age Related Macular Degeneration and Sensorineural Hearing Loss

Medicina, 2022
The pathogeneses of age-related macular degeneration (AMD) and age-related hearing impairment are not yet fully understood. If AMD and age-related hearing impairment are correlated, the cause of both may be a result of a common vulnerability.
Marina Istrate, Mihai Hasbei-Popa, Daniela Adriana Iliescu, Ana Cristina Ghiță, Brigitha Vlaicu, Mihai Aurelian Ghiță   +5 more
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Open innovation in neuroscience research and drug discovery

Brain and Neuroscience Advances, 2018
The pressures on the pharmaceutical industry have incentivised a number of new collaborative models of research and development which can be categorised as open innovation.
Ann J. Hunter, Wen H. Lee, Chas Bountra
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Novel rodent models for macular research [PDF]

, 2010
BACKGROUND: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Gesine Huber, Muehlfriedel, Regine, Huber, G., Feng, Yuxi, Seeliger, M., Tanimoto, Naoyuki, Tanimoto Naoyuki, Severin Heynen, Hans-Peter Hammes, Christian Grimm, Feng, Y., Imsand Coni, Imsand, Coni, Muehlfriedel Regine, Susanne C. Beck, Huber, Gesine, Heynen, S., Grimm Christian, Regine Muehlfriedel, Huber Gesine, vom Hagen Franziska, Coni Imsand, Imsand, C., Seeliger Mathias W., Mühlfriedel, R., Peichl, Leo, Mathias W Seeliger, vom Hagen, F., Mühlfriedel, Regine, Tanimoto, N., Heynen Severin, Hammes, Hans-Peter, Seeliger, Mathias W, Beck Susanne C., Seeliger, Mathias W., Peichl Leo, Yuxi Feng, Peichl, L., Beck, Susanne C; https://orcid.org/, Grimm, C., Feng Yuxi, Mathias W. Seeliger, Leo Peichl, Franziska vom Hagen, Grimm, Christian, Grimm, Christian; https://orcid.org/, vom Hagen, Franziska, Beck, S., Beck, Susanne Christiane, Hammes Hans-Peter, Susanne C Beck, Naoyuki Tanimoto, Hammes, H., Heynen, Severin   +53 more
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