Results 41 to 50 of about 340,047 (304)
, 2009 PURPOSE: To investigate whether variation in the distribution of the risk allele frequency of the Y402H single-nucleotide polymorphism (SNP) across various ethnicities and geographic regions reflects differences in the prevalence of late age-related ...
Whittaker, John C +9 more
core +1 more source
A Population-Based Ultra-Widefield Digital Image Grading Study for Age-Related Macular Degeneration-Like Lesions at the Peripheral Retina. [PDF]
, 2015 Our understanding of the relevance of peripheral retinal abnormalities to disease in general and in age-related macular degeneration (AMD) in particular is limited by the lack of detailed peripheral imaging studies.
Florea, D +6 more
core
Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation
Advanced Materials Technologies, EarlyView.Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching +9 more
wiley +1 more source
Cost-effectiveness of smoking cessation to prevent age-related macular degeneration
Cost Effectiveness and Resource Allocation, 2008 Background Tobacco smoking is a risk factor for age-related macular degeneration, but studies of ex-smokers suggest quitting can reduce the risk. Methods We fitted a function predicting the decline in risk of macular degeneration after quitting to data ...
Matthews Jane P +2 more
doaj +1 more source
Age-related macular degeneration: current treatments [PDF]
, 2009 Jean Pierre Hubschman, Shantan Reddy, Steven D SchwartzJules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USAPurpose: Although important progress has been made in ...
Jean Pierre Hubschman +5 more
core +1 more source
, 2021 Purpose: The aim of the current study was to investigate the correlation between the pretreatment aqueous level of vascular endothelial growth factor (VEGF) and clinical activity in neovascular age-related macular degeneration.Methods: Patients with ...
0000-0001-9645-3837 +34 more
core +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Coexistence of Peripheral Retinal Diseases with Macular Hole
Türk Oftalmoloji Dergisi, 2019 Objectives:To investigate the frequency of retinal tear, retinal hole, and lattice degeneration in peripheral retinal examination of patients with macular hole.Materials and Methods:The files of patients who underwent pars plana vitrectomy surgery with a
Erdoğan Yaşar +3 more
doaj +1 more source
Juvenile Macular Degenerations [PDF]
Seminars in Pediatric Neurology, 2017 In this article, we review the following 3 common juvenile macular degenerations: Stargardt disease, X-linked retinoschisis, and Best vitelliform macular dystrophy. These are inherited disorders that typically present during childhood, when vision is still developing.
Altschwager P. +4 more
openaire +4 more sources