Results 61 to 70 of about 285,624 (259)

THE CORRELATION BETWEEN AQUEOUS VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL AND CLINICAL ACTIVITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

, 2021
Purpose: The aim of the current study was to investigate the correlation between the pretreatment aqueous level of vascular endothelial growth factor (VEGF) and clinical activity in neovascular age-related macular degeneration.Methods: Patients with ...
0000-0001-9645-3837, 10749021, 7444, SAISHIN, Yoshitsugu, 大路, 正人, SAWADA, Tomoko, OHJI, Masahito, 澤田, 修, 2767, 2502, 00378465, SAWADA, Osamu, 6625, 一山, 悠介, 90252650, 80531516, 30379193, 澤田, 智子, 7692, 西信, 良嗣, ICHIYAMA, Yusuke, 7250, 90814848, 3728, 0000-0002-9134-9886, 柿木, 雅志, 小幡, 峻平, 0000-0001-9752-0499, OBATA, Shumpei, 伊藤, 友香, 0000-0002-9828-4288, 2737, 0000-0001-6120-2392, ITO, Yuka, KAKINOKI, Masashi   +34 more
core   +1 more source

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

Clinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Artificial Intelligence in Optical Coherence Tomography‐Based Ophthalmic Imaging: From Automated Diagnosis to Personalized Disease Monitoring

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly applied to optical coherence tomography (OCT) in ophthalmology, but evidence for automated diagnosis is stronger than evidence for longitudinal monitoring. This narrative review evaluates OCT‐based AI with emphasis on disease monitoring and progression, particularly in retinal disease and glaucoma ...
Stjepan Škudar
wiley   +1 more source

Avaliação dos efeitos adversos desencadeados pelo uso de difosfato de cloroquina, com ênfase na retinotoxicidade, em 350 doentes com lúpus eritematoso Evaluation of adverse events triggered by the use of chloroquine diphosphate, emphasis on retina toxicity, in 350 patients with lupus erythematosus

Anais Brasileiros de Dermatologia, 2005
FUNDAMENTOS: A ocorrência de retinopatia pela cloroquina vem diminuindo em todo o mundo, com poucos estudos brasileiros sobre o problema. OBJETIVOS: Compreender melhor a fisiopatologia das reações tipo 1.
Maria Raquel Nogueira C. Ponchet, Maria Apparecida C. Vilela, Karen Krist Suni Sinahara, Patrícia de Freitas Dotto   +3 more
doaj   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Real world pharmacovigilance assessment of drug related macular degeneration risks

Scientific Reports
Macular degeneration is a leading cause of irreversible vision loss, significantly impacting quality of life. To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data ...
Xiaodong Chen, Shinan Wu, Shaopan Wang, Chaofeng Yu, Zihan Guo, Shiya Huang, Peixin Cai, Yanliang Miao, Shiying Li, Qian Chen   +9 more
doaj   +1 more source

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

The Lancet Global Health, 2014
Background: Numerous population-based studies of age-related macular degeneration have been reported around the world, with the results of some studies suggesting racial or ethnic differences in disease prevalence.
Wan Ling Wong, MBiostat, Xinyi Su, MD, Xiang Li, BSc, Chui Ming G Cheung, MD, Ronald Klein, MD, Dr. Ching-Yu Cheng, MD, Prof. Tien Yin Wong, MBBS   +6 more
doaj   +1 more source

Ranibizumab and pegaptanib for the treatment of age-related macular degeneration: a systematic review and economic evaluation

, 2008
Objectives: to assess the clinical effectiveness and cost-effectiveness of ranibizumab and pegaptanib for subfoveal choroidal neovascularisation (CNV) associated with wet age-related macular degeneration (AMD).Data sources: electronic databases were ...
Price, A., A Takeda, Jones, J., S Tan, Clegg, A.J., A Price, Colquitt, J.L., Tan, S.C., Takeda, A.L., J Colquitt, J Jones, A Clegg   +11 more
core   +1 more source

Precision Mapping of Retinal Disease: Identification of Differential Progression Trajectories via Imaging Phenomics

iMetaMed, EarlyView.
Applying single‐cell RNA‐seq techniques to large‐scale clinical phenotypic data enables the discovery of differential disease progression trajectories and the construction of data‐driven progression scores. These can then be integrated into precision medicine studies to investigate the drivers of patient‐specific disease outcomes. ABSTRACT We propose a
Christian Anderson, Liam Scott, Irene Leung, Ferenc Sallo, Catherine Egan, Tunde Peto, The MacTel Consortium, Melanie Bahlo, Martin Friedlander, Simone Tzaridis, Lea Scheppke, Roberto Bonelli   +11 more
wiley   +1 more source