Results 71 to 80 of about 340,047 (304)

The Multiple Criteria Qualitative Value‐Based Pricing Framework “MARIE” for Novel Cell and Gene Therapy

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley   +1 more source

Avaliação dos efeitos adversos desencadeados pelo uso de difosfato de cloroquina, com ênfase na retinotoxicidade, em 350 doentes com lúpus eritematoso Evaluation of adverse events triggered by the use of chloroquine diphosphate, emphasis on retina toxicity, in 350 patients with lupus erythematosus

open access: yesAnais Brasileiros de Dermatologia, 2005
FUNDAMENTOS: A ocorrência de retinopatia pela cloroquina vem diminuindo em todo o mundo, com poucos estudos brasileiros sobre o problema. OBJETIVOS: Compreender melhor a fisiopatologia das reações tipo 1.
Maria Raquel Nogueira C. Ponchet   +3 more
doaj   +1 more source

Post‐ovipositional staging series of the foveate, gold‐dust day gecko, Phelsuma laticauda (Gekkota: Squamata)

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Disorders affecting the fovea, a specialized pit in the human retina necessary for high acuity vision, represent a significant healthcare burden across the globe. Degenerative diseases (e.g., macular degeneration) and developmental conditions (e.g., albinism and aniridia) affecting the fovea can lead to irreversible, central vision ...
Andrew E. Wegerski   +6 more
wiley   +1 more source

Correlation between social support and quality of life in age related macular degeneration

open access: yesHuli yanjiu, 2017
Objective:To investigate the status quo of visual related quality of life and social support in agerelated macular degeneration patients,and to explore the relationship between them.Methods:Quality of life and social support were evaluated in 120 ...
李姝   +4 more
doaj  

Real world pharmacovigilance assessment of drug related macular degeneration risks

open access: yesScientific Reports
Macular degeneration is a leading cause of irreversible vision loss, significantly impacting quality of life. To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data ...
Xiaodong Chen   +9 more
doaj   +1 more source

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

open access: yesThe Lancet Global Health, 2014
Background: Numerous population-based studies of age-related macular degeneration have been reported around the world, with the results of some studies suggesting racial or ethnic differences in disease prevalence.
Wan Ling Wong, MBiostat   +6 more
doaj   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Artificial Intelligence in Optical Coherence Tomography‐Based Ophthalmic Imaging: From Automated Diagnosis to Personalized Disease Monitoring

open access: yesEye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is increasingly applied to optical coherence tomography (OCT) in ophthalmology, but evidence for automated diagnosis is stronger than evidence for longitudinal monitoring. This narrative review evaluates OCT‐based AI with emphasis on disease monitoring and progression, particularly in retinal disease and glaucoma ...
Stjepan Škudar
wiley   +1 more source

Postharvest Management to Preserve the Nutritional Quality of Vegetables: An Overview Based on Current Research Findings Across the Globe

open access: yesFuture Postharvest and Food, EarlyView.
Postharvest losses in vegetables extend beyond mere quantitative reduction through physical deterioration and spoilage; they encompass substantial qualitative degradation, particularly the deterioration of critical nutritional constituents. Following harvest, vegetables maintain metabolic activity, and when subjected to suboptimal environmental ...
Md. Abdul Kader   +4 more
wiley   +1 more source

Nutrients for Prevention of Macular Degeneration and Eye-Related Diseases

open access: yesAntioxidants, 2019
The risk of macular degeneration can be reduced through the consumption of antioxidant-rich foods, supplements, and nutraceutical formulas. This review focuses on the antioxidants, vitamins, and minerals that have been reported for reducing the risk of ...
Hock Eng Khoo   +4 more
doaj   +1 more source

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