Results 21 to 30 of about 81,968 (264)

Recent advances of exosomes in age-related macular degeneration

Frontiers in Pharmacology, 2023
Exosomes are 30–150 nm extracellular vesicles that are secreted by almost all types of cells. Exosomes contain a variety of biologically active substances, such as proteins, nucleic acids, and lipids, and are important in the intercellular communication ...
Feng Gu, Jiyu Jiang, Peng Sun
doaj   +1 more source

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review

Oftalʹmologiâ, 2023
Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of ...
A. N. Kulikov, M. V. Zakharov, A. A. Volozhev   +2 more
doaj   +1 more source

FAMILIAL MACULAR DEGENERATION [PDF]

The Journal of Nervous and Mental Disease, 1919
n ...
openaire   +1 more source

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

Health Technology Assessment, 2022
Background: Neovascular age-related macular degeneration is a leading cause of sight loss, and early detection and treatment is important. For patients with neovascular age-related macular degeneration in one eye, it is usual practice to monitor the ...
Katie Banister, Jonathan A Cook, Graham Scotland, Augusto Azuara-Blanco, Beatriz Goulão, Heinrich Heimann, Rodolfo Hernández, Ruth Hogg, Charlotte Kennedy, Sobha Sivaprasad, Craig Ramsay, Usha Chakravarthy   +11 more
doaj   +1 more source

Autophagy Impairment in Retinal Ganglion Cells Following Hypoglycemia in Mice

Cells
(1) Background: Diabetic retinopathy (DR), caused by hypo- and hyperglycaemia, is the leading cause of blindness. Hypoglycemia induces endoplasmic reticulum stress and retinal cell death in mice, and low-glucose conditions induce macroautophagy/autophagy
Daria Fresia, Enrica Cannizzaro, Angelica Borgo, Marc Schwab, Raphaël Roduit   +4 more
doaj   +1 more source

Age- and sex-based evaluation of the association between refractive error and age-related macular degeneration in the Korean population.

PLoS ONE, 2020
PURPOSE:The aim of this study was to investigate the association between refractive error and prevalence of age-related macular degeneration (AMD) in Korean adults, based on the sex and age group.
Kook Lee, Jin-Woo Kwon, Wan Jin Jahng, Young-Hoon Park, Donghyun Jee   +4 more
doaj   +1 more source

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Cost-effectiveness of smoking cessation to prevent age-related macular degeneration

Cost Effectiveness and Resource Allocation, 2008
Background Tobacco smoking is a risk factor for age-related macular degeneration, but studies of ex-smokers suggest quitting can reduce the risk. Methods We fitted a function predicting the decline in risk of macular degeneration after quitting to data ...
Matthews Jane P, Hurley Susan F, Guymer Robyn H   +2 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source