Results 31 to 40 of about 285,624 (259)

Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study

Health Technology Assessment, 2022
Background: Neovascular age-related macular degeneration is a leading cause of sight loss, and early detection and treatment is important. For patients with neovascular age-related macular degeneration in one eye, it is usual practice to monitor the ...
Katie Banister, Jonathan A Cook, Graham Scotland, Augusto Azuara-Blanco, Beatriz Goulão, Heinrich Heimann, Rodolfo Hernández, Ruth Hogg, Charlotte Kennedy, Sobha Sivaprasad, Craig Ramsay, Usha Chakravarthy   +11 more
doaj   +1 more source

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review

Oftalʹmologiâ, 2023
Age related macular degeneration is a leading cause of vision loss and an increasing problem of disability throughout the world among adults. That revue covers historical points, risk factors, pathogenesis, classification and current treatment ways of ...
A. N. Kulikov, M. V. Zakharov, A. A. Volozhev   +2 more
doaj   +1 more source

Autophagy Impairment in Retinal Ganglion Cells Following Hypoglycemia in Mice

Cells
(1) Background: Diabetic retinopathy (DR), caused by hypo- and hyperglycaemia, is the leading cause of blindness. Hypoglycemia induces endoplasmic reticulum stress and retinal cell death in mice, and low-glucose conditions induce macroautophagy/autophagy
Daria Fresia, Enrica Cannizzaro, Angelica Borgo, Marc Schwab, Raphaël Roduit   +4 more
doaj   +1 more source

Age- and sex-based evaluation of the association between refractive error and age-related macular degeneration in the Korean population.

PLoS ONE, 2020
PURPOSE:The aim of this study was to investigate the association between refractive error and prevalence of age-related macular degeneration (AMD) in Korean adults, based on the sex and age group.
Kook Lee, Jin-Woo Kwon, Wan Jin Jahng, Young-Hoon Park, Donghyun Jee   +4 more
doaj   +1 more source

Age-related macular degeneration in the UK [PDF]

The aim of this thesis was to investigate the prevalence and impact of age-related macular degeneration (AMD) causing visual impairment in people aged 75 years and above in the UK.
Evans, Jennifer Rosemary
core   +1 more source

An Ecological Correlation Study of Late Age-Related Macular Degeneration and the Complement Factor H Y402H Polymorphism

, 2009
PURPOSE: To investigate whether variation in the distribution of the risk allele frequency of the Y402H single-nucleotide polymorphism (SNP) across various ethnicities and geographic regions reflects differences in the prevalence of late age-related ...
Whittaker, John C, Sofat, Reecha, Smeeth, Liam, Nonyane, Bareng A.S., Chakravarthy, Usha, Fletcher, Astrid E., Whittaker, John C., Fletcher, Astrid E, Nitsch, Dorothea, Nonyane, Bareng AS   +9 more
core   +1 more source

Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]

, 2012
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger, Yu, Alice L., Burger, Johannes, Welge-Lussen, Ulrich, Alice L Yu, Kerstin Birke, Birke, Kerstin, Alice L. Yu, Ulrich Welge-Lussen   +8 more
core   +2 more sources

Association of sildenafil use with age-related macular degeneration: a retrospective cohort study

BMJ Open Ophthalmology
Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of ...
Nicola Jaime Adderley, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Alastair K Denniston, Wen Hwa Lee, Ji Eun Diana Han, Jesse Coker   +6 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Cost-effectiveness of smoking cessation to prevent age-related macular degeneration

Cost Effectiveness and Resource Allocation, 2008
Background Tobacco smoking is a risk factor for age-related macular degeneration, but studies of ex-smokers suggest quitting can reduce the risk. Methods We fitted a function predicting the decline in risk of macular degeneration after quitting to data ...
Matthews Jane P, Hurley Susan F, Guymer Robyn H   +2 more
doaj   +1 more source