Results 51 to 60 of about 108,706 (253)

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

Advanced Science, EarlyView.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie, Mengyan Zhu, Zhongxian Zhu, Jiaqi Tang, Ruyi Zhang, Zequan Ding, Junzhi Li, Zhongluan Wu, Paul Kwong Hang Tam, Qianghu Wang, Vincent Chi Hang Lui, Yankai Xia, Weibing Tang   +12 more
wiley   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

VLDLR gene polymorphism associated with abdominal fat in Gaoyou domestic duck breed

Czech Journal of Animal Science, 2015
VLDLR gene was chosen as a candidate gene influencing abdominal fat trait and body weight due to previous studies in human and mouse. Herein, the objectives of this study were to identify genetic polymorphisms of duck VLDLR gene, and to analyze ...
N.N. Zhao, S. Lin, Z.Q. Wang, T.J. Zhang
doaj   +1 more source

Framing National Education in Hong Kong: A frame analysis of power dynamics in stakeholders' competing narratives

British Educational Research Journal, EarlyView.
Abstract This article examines how national education in Hong Kong functions as a contested arena in which state and non‐state actors struggle over the meaning of citizenship, identity and schooling. Using inductive frame analysis of 319 news articles (2020–2025) from five Chinese‐ and English‐language outlets, it identifies diagnostic, prognostic and ...
Jason Cong Lin
wiley   +1 more source

A Single-Step Immunocapture Assay to Quantify HCC Exosomes Using the Highly Sensitive Fluorescence Nanoparticle-Tracking Analysis

Journal of Hepatocellular Carcinoma, 2023
Ali Riza Koksal,1 Nergiz Ekmen,2 Yucel Aydin,2 Kelley Nunez,3 Tyler Sandow,4 Molly Delk,2 Martin Moehlen,2 Paul Thevenot,3 Ari Cohen,3,5 Srikanta Dash1,2,6 1Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New ...
Koksal AR, Ekmen N, Aydin Y, Nunez K, Sandow T, Delk M, Moehlen M, Thevenot P, Cohen A, Dash S   +9 more
doaj  

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1

Chemistry – A European Journal, EarlyView.
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee   +5 more
wiley   +1 more source

Heterogeneities of Site-Specific N-Glycosylation in HCC Tumors With Low and High AFP Concentrations

Frontiers in Oncology, 2020
Hepatocellular carcinoma (HCC) is still one of the malignant tumors with high morbidity and mortality in China and worldwide. Although alpha-fetoprotein (AFP) as well as core fucosylated AFP-L3 have been widely used as important biomarkers for HCC ...
Ting Zhao, Liyuan Jia, Jun Li, Chen Ma, Jingyu Wu, Jiechen Shen, Liuyi Dang, Bojing Zhu, Pengfei Li, Y. Zhi, Rongxia Lan, Yintai Xu, Z. Hao, Yichao Chai, Qingshan Li, Liangshuo Hu, Shisheng Sun   +16 more
semanticscholar   +1 more source

Clathrate hydrate crystallization

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Clathrate hydrate crystallization has been an area of interest to chemical engineers from the point of view of crystal structure, thermophysical properties, phase equilibria, kinetics, industrial applications, and environmental (climate change) implications.
Peter Englezos
wiley   +1 more source

Machine Learning Based Predictive Model for AFP-Based Unidirectional Composite Laminates

IEEE Transactions on Industrial Informatics, 2020
Manufacturing of composites using automated fiber placement (AFP) is a complex process that involves large number of processing conditions and variables.
Chathura Wanigasekara, E. Oromiehie, A. Swain, B., G. Prusty, S. Nguang   +5 more
semanticscholar   +1 more source

Mapping the US Bridgebuilding Field: Situating Organizations in the Ecosystem of Social Change

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article explores the ecosystem of bridge‐building initiatives in the United States. Drawing on an original database of 223 organizations, interviews with 7 staff across 6 organizations, and a literature review related to bridge‐building, polarization, and collective action, we first describe the range of existing initiatives and their ...
Gabrielle Mathews, Karen Ross
wiley   +1 more source