Results 71 to 80 of about 108,706 (253)

The predictive role of estrogen, FSH, and LH in combination with biomarkers for early ovarian cancer detection

Mìžnarodnij Endokrinologìčnij Žurnal
Background. The early detection of ovarian cancer is not easy, and the predictive value of hormonal (estrogen, follicle-stimulating hormone (FSH), luteinizing hormone (LH)) and molecular biomarkers can be used to facilitate the diagnosis and patient ...
Bayadir Abdul Hussein Mahameed, Hadel Kareem Al-Rubaiawi, Maha H. Ahmed, Osama A. Mohsein   +3 more
doaj   +1 more source

Biochemical markers for prediction of hypertensive disorders of pregnancy [PDF]

Journal of Medical Biochemistry, 2019
Background: Gestational hypertension (GH) and preeclampsia (PE) are the most common gestational complications. Several placental biochemical markers are used to predict GH/PE, but with conflicting results.
Kocijančić-Belović Dusica, Plešinac Snežana, Dotlić Jelena, Savić-Radojević Ana, Akšam Slavica, Marjanović-Cvjetićanin Mirjana, Kocijančić Aleksandar   +6 more
doaj  

The prognostic correlation of AFP level at diagnosis with pathological grade, progression, and survival of patients with hepatocellular carcinoma

Scientific Reports, 2017
The purpose of this study was to conduct a comprehensive study of the clinical correlation between the alpha-fetoprotein (AFP) level at diagnosis and pathological grades, progression, and survival of patients with hepatocellular carcinoma (HCC).
Dou-sheng Bai, Chi Zhang, Ping Chen, Sheng-jie Jin, Guo-qing Jiang   +4 more
semanticscholar   +1 more source

The use of biomarkers GP-73 and AFP in the early diagnosis of hepatocarcinoma associated with liver cirrhosis of HCV etiology

Журнал инфектологии
Purpose: comparative study of the informativeness of tumor markers GP-73 and AFP in the early diagnosis of hepatocellular carcinoma associated with liver cirrhosis of HCV etiology.Materials and methods: In the study, 71 people were divided into 4 groups.
A. K. Bayjanov, U. Yu. Ismоilov, A. S. Khikmatullaeva, Kh. P. Nasirova, J. A. Anvarov, Ch. B. Turaeva   +5 more
doaj   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Development and Validation of a Prognostic Nomogram in AFP-negative hepatocellular carcinoma

International Journal on Biological Sciences, 2019
The aim of this study is to establish and validate an effective prognostic nomogram in patients with AFP-negative hepatocellular carcinoma (HCC). The nomogram was based on a primary cohort that consisted of 419 patients with clinicopathologically ...
Xueping Wang, M. Mao, Zhonglian He, Lin Zhang, Huilan Li, Jianhua Lin, Yimeng He, Shuqin Dai, Wanming Hu, Wanli Liu   +9 more
semanticscholar   +1 more source

Serum Midkine as a Biomarker for Hepatocellular Carcinoma Treatment Response and Prognostication

Journal of Clinical Laboratory Analysis, EarlyView.
Up‐to‐date, tumor markers are considered more helpful in the evaluation of treatment response and prognostication rather than diagnosis. Identifying a valid biomarker to help clinical management of hepatocellular carcinoma (HCC) is still a challenge, especially the alpha‐fetoprotein (AFP) negative HCC. This study evaluated the efficacy of serum Midkine
Yanfang Luo, Qiuwei Lu, Jing Huang, Liejun Jiang   +3 more
wiley   +1 more source

MicroRNAs as Appropriate Discriminators in Non-Specific Alpha-Fetoprotein (AFP) Elevation in Testicular Germ Cell Tumor Patients

Non-Coding RNA, 2020
Testicular germ cell tumors (TGCTs) are the most commonly diagnosed malignancies in younger men. The monitoring of disease course and recurrence is supported by traditional tumor markers, including α-fetoprotein (AFP).
Anna L. Lembeck, Philip Puchas, Georg Hutterer, Dominik A. Barth, Angelika Terbuch, Thomas Bauernhofer, Martin Pichler   +6 more
doaj   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

Itching for a diagnosis: Dysesthesias as an atypical presentation of Wilson disease in an adolescent—Case report

JPGN Reports, EarlyView.
Abstract Wilson disease (WD) is an autosomal recessive disorder of hepatic copper metabolism with varied clinical presentations. We describe a 15‐year‐old male referred for elevated aminotransferases, burning facial pruritis, scalp dysesthesias, and chronic bilateral lower extremity edema.
Tierra L. R. Mosher, John Hicks, Krupa R. Mysore   +2 more
wiley   +1 more source