Results 71 to 80 of about 175,800 (301)

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

The use of biomarkers GP-73 and AFP in the early diagnosis of hepatocarcinoma associated with liver cirrhosis of HCV etiology

Журнал инфектологии
Purpose: comparative study of the informativeness of tumor markers GP-73 and AFP in the early diagnosis of hepatocellular carcinoma associated with liver cirrhosis of HCV etiology.Materials and methods: In the study, 71 people were divided into 4 groups.
A. K. Bayjanov, U. Yu. Ismоilov, A. S. Khikmatullaeva, Kh. P. Nasirova, J. A. Anvarov, Ch. B. Turaeva   +5 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G., Göbel, U., Haas, R. J., Schmidt, P., Schneider, D. T.   +4 more
core   +1 more source

Standardized Management Pathway to Prevent Acute Rejection After Liver Transplantation Following ICI Therapy for Downstaging HCC

Health Care Science, EarlyView.
Findings indicate that within a standardized clinical pathway integrating structured immunosuppression, therapeutic drug monitoring, and early complication surveillance, liver transplantation after ICI exposure can be performed safely without increased rejection risk.
Ning Wang, Zebin Zhu, Hao Zheng, Can Qi, Xiaodong Yuan, Xuefeng Li, Zhijun Xu, Jiwei Qin, Wei Wu, Jizhou Wang, Ruipeng Song, Zhiyong Guo, Lianxin Liu, Shu‐Geng Zhang, Björn Nashan   +14 more
wiley   +1 more source

Evaluation of tumor markers for the detection of hepatocellular carcinoma in Yangon General Hospital, Myanmar. [PDF]

, 2002
Levels of alpha-fetoprotein (AFP), its glycoforms AFP-L3 and AFP-P4, and proteins induced by vitamin K absence or antagonist-II (PIVKA-II) were determined in sera obtained from patients in Yangon General Hospital (20 with hepatocellular carcinoma (HCC ...
Hlaing, Naomi Khaing Than, Okada, Shigeru, Taketa, Kazuhisa, Win, Khin Maung, Win, Ne   +4 more
core   +1 more source

MicroRNAs as Appropriate Discriminators in Non-Specific Alpha-Fetoprotein (AFP) Elevation in Testicular Germ Cell Tumor Patients

Non-Coding RNA, 2020
Testicular germ cell tumors (TGCTs) are the most commonly diagnosed malignancies in younger men. The monitoring of disease course and recurrence is supported by traditional tumor markers, including α-fetoprotein (AFP).
Anna L. Lembeck, Philip Puchas, Georg Hutterer, Dominik A. Barth, Angelika Terbuch, Thomas Bauernhofer, Martin Pichler   +6 more
doaj   +1 more source

Abnormal prothrombin (DES-y-Carboxy Prothrombin) in hepatocellular carcinoma [PDF]

, 1991
Des-γ-carboxy prothrombin (DCP), a protein induced by vitamin K absence or antagonist-II (PIVKA-II) was measured by an enzyme immunoassay (E-1023) using anti-DCP monoclonal antibody in 92 patients with various hepatobiliary diseases. Thirty-six of the 38
Carr, B, Iwaki, Y, Iwatsuki, S, Nakao, A, Starzl, E, Virji, A   +5 more
core  

Immunohistochemical analysis of metastasising hepatocellular carcinomas in dogs

Veterinární Medicína, 2016
In this study, the immunohistochemical features of primary hepatocellular carcinomas and their metastases in visceral organs, including the lungs, spleen and kidneys were examined using antibodies against carcino-embryonic antigen (CEA) cytokeratin (CK ...
R. Ciaputa, P. Bandoch, K. Lewandowska, J.A. Madej, M. Kandefer-Gola, I. Janus, M. Nowak   +6 more
doaj   +1 more source

Adverse Pregnancy Outcomes by Degree of Maternal Serum Analyte Elevation: A Retrospective Cohort Study

American Journal of Perinatology Reports, 2020
Objective The aim of this study was to evaluate rates of preterm birth (PTB) and obstetric complication with maternal serum analytes > 2.5 multiples of the median (MoM) by degree of elevation.
Amanda Yeaton-Massey, Rebecca J. Baer, Larry Rand, Laura L. Jelliffe-Pawlowski, Deirdre J. Lyell   +4 more
doaj   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source