Results 131 to 140 of about 1,681,802 (268)

Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5 [PDF]

, 2012
At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement
Büscher, P., Guisez, Y., Lejon, V., Rogé, S., Van Nieuwenhove, L.   +4 more
core   +1 more source

The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense

PLoS Neglected Tropical Diseases, 2017
Background Important control efforts have led to a significant reduction of the prevalence of human African trypanosomiasis (HAT) in Côte d’Ivoire, but the disease is still present in several foci.
M. N’Djetchi, H. Ilboudo, M. Koffi, J. Kaboré, J. Kaboré, D. Kaba, F. Courtin, B. Coulibaly, Pierre Fauret, L. Kouakou, S. Ravel, S. Deborggraeve, P. Solano, T. de Meeûs, B. Bucheton, V. Jamonneau   +15 more
semanticscholar   +1 more source

Through the dark continent: African trypanosome development in the tsetse fly [PDF]

, 2013
African trypanosomes are unicellular flagellated parasites causing trypanosomiases in Africa, a group of severe diseases also known as sleeping sickness in human and nagana in cattle.
Rotureau, Brice, Van Den Abbeele, Jan
core   +4 more sources

A preliminary serological study of Trypanosoma evansi and Trypanosoma lewisi in a Chinese human population [PDF]

, 2018
Trypanosoma evansi, known as an animal trypanosome, is widely distributed in many countries of Africa, Asia and South America; it causes significant economic loss in these countries.
Courtois, Patrick, Desquesnes, Marc, Gao, Jiang-Mei, Jittapalapong, Sathaporn, Li, Su-Jin, Lun, Zhao-Rong, Truc, Philippe, Vincendeau, Philippe, Zhang, Xuan   +8 more
core   +1 more source

Enhanced passive screening and diagnosis for gambiense human African trypanosomiasis in north-western Uganda – Moving towards elimination

PLoS ONE, 2017
Introduction The incidence of gambiense human African trypanosomiasis (gHAT) in Uganda has been declining, from 198 cases in 2008, to only 20 in 2012. Interruption of transmission of the disease by early diagnosis and treatment is core to the control and
C. Wamboga, E. Matovu, P. Bessell, A. Picado, S. Biéler, J. Ndung'u   +5 more
semanticscholar   +1 more source

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

Frontiers in Immunology, 2018
African trypanosomosis (AT) is a chronically debilitating parasitic disease of medical and economic importance for the development of sub-Saharan Africa.
B. Stijlemans, P. De Baetselier, S. Magez, J. V. Van Ginderachter, C. De Trez   +4 more
semanticscholar   +1 more source

Risk for Human African Trypanosomiasis, Central Africa, 2000–2009

Emerging Infectious Diseases, 2011
Comprehensive georeference records for human African trypanosomiasis in Cameroon, Central African Republic, Chad, Congo, Equatorial Guinea, and Gabon were combined with human population layers to estimate a kernel-smoothed relative risk function.
Pere P. Simarro, Giuliano Cecchi, José R. Franco, Massimo Paone, Eric M. Fèvre, Abdoulaye Diarra, José Antonio Ruiz Postigo, Raffaele C. Mattioli, Jean G. Jannin   +8 more
doaj   +1 more source

The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question [PDF]

, 2017
Human African trypanosomiasis (HAT), also known as sleeping sickness, puts millions of people at risk in sub-Saharan Africa and is a neglected parasitic disease that is almost always fatal if untreated or inadequately treated. HAT manifests itself in two
Gettinby, George, Kennedy, Peter G.E., Njamnshi, Alfred K.   +2 more
core   +1 more source

Brain‐Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis

ChemMedChem, 2018
In vitro whole‐organism screens of Trypanosoma brucei with representative examples of brain‐penetrant microtubule (MT)‐stabilizing agents identified lethal triazolopyrimidines and phenylpyrimidines with sub‐micromolar potency.
Ludovica Monti, Steven C Wang, Killian Oukoloff, Amos B. Smith, K. Brunden, C. Caffrey, C. Ballatore   +6 more
semanticscholar   +1 more source

Iloprost treatment enhanced IL-4 signalling to reverse trypanosome-induced cognitive deficits and suppressed neuroinflammation in mice

International Journal of Infectious Diseases
Introduction: The development of neurological disorders following trypanosome brain infection has been recognised for over a century. However, an ongoing endeavour persists to comprehensively understand the neurocognitive and neuropathological changes ...
Dr Oluwashola Olaolu, Professor Hajierah Davids, Professor Gill. B Dealtry, Miss Oluwatoyin Morenikeji, Dr Emmanuel T Obishakin, Mrs Binta Iliayasu, Dr Azeez Idris, Dr Chris Duyilemi Ajonijebu   +7 more
doaj   +1 more source