Results 1 to 10 of about 22,393 (137)

Molecular Identification of ABC2 Transporter Gene Encode Protein Ngawi Trypanosoma evansi Isolate that suspected resistance to Isometamidium Chloride [PDF]

BIO Web of Conferences, 2021
This study aims to determine the profile of the ABC2 encoding transporter on Trypanosoma evansi (T. evansi) Ngawi isolates, Indonesia, exposed with Isometamidium Chloride (ISM). This study used blood samples of mice containing Trypanosoma evansi that had
Wusahaningtyas Lu’lu’ Sahara, Nuryady Moh Mirza, Firdausy Lintang Winantya, Fahrurrozi Zs Ahmad, Nurcahyo R. Wisnu   +4 more
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Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa

Frontiers in Veterinary Science, 2021
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi, Keneth Iceland Kasozi, Gerald Zirintunda, Fred Ssempijja, Bridget Buyinza, Khalid J. Alzahrani, Kevin Matama, Helen N. Nakimbugwe, Helen N. Nakimbugwe, Luay Alkazmi, David Onanyang, Paul Bogere, Juma John Ochieng, Saher Islam, Wycliff Matovu, David Paul Nalumenya, Gaber El-Saber Batiha, Lawrence Obado Osuwat, Mahmoud Abdelhamid, Tianren Shen, Tianren Shen, Leonard Omadang, Susan Christina Welburn, Susan Christina Welburn   +23 more
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Visualisation of experimentally determined and predicted protein N-glycosylation and predicted glycosylphosphatidylinositol anchor addition in Trypanosoma brucei. [version 1; peer review: 3 approved]

Wellcome Open Research, 2022
Background: Trypanosoma brucei is a protozoan parasite and the etiological agent of human and animal African trypanosomiasis. The organism cycles between its mammalian host and tsetse vector.
Michael A. J. Ferguson, Michele Tinti
doaj   +1 more source

Therapeutic Strategies against Leishmania and Trypanosoma

Pathogens, 2023
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos, Igor A. Rodrigues, Claudia M. d’Avila-Levy, Cátia L. Sodré, Koert Ritmeijer, Marta H. Branquinha   +5 more
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Ribose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivity. [PDF]

PLoS Neglected Tropical Diseases, 2015
Ribose 5-phosphate isomerase is an enzyme involved in the non-oxidative branch of the pentose phosphate pathway, and catalyzes the inter-conversion of D-ribose 5-phosphate and D-ribulose 5-phosphate.
Inês Loureiro, Joana Faria, Christine Clayton, Sandra Macedo-Ribeiro, Nuno Santarém, Nilanjan Roy, Anabela Cordeiro-da-Siva, Joana Tavares   +7 more
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Wild chimpanzees are infected by Trypanosoma brucei

International Journal for Parasitology: Parasites and Wildlife, 2015
Although wild chimpanzees and other African great apes live in regions endemic for African sleeping sickness, very little is known about their trypanosome infections, mainly due to major difficulties in obtaining their blood samples.
Milan Jirků, Jan Votýpka, Klára J. Petrželková, Kateřina Jirků-Pomajbíková, Eva Kriegová, Roman Vodička, Felix Lankester, Siv Aina J. Leendertz, Roman M. Wittig, Christophe Boesch, David Modrý, Francisco J. Ayala, Fabian H. Leendertz, Julius Lukeš   +13 more
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The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

International Journal for Parasitology: Drugs and Drug Resistance, 2019
The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography.
Anthonius A. Eze, John Igoli, Alexander I. Gray, Graham G. Skellern, Harry P. De Koning   +4 more
doaj   +1 more source

Antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection

Open Veterinary Science, 2022
This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.
Chukwu Ifeoma L., Ugwu Malachy C., Iroha Ifeanyi R., Mbagwu Ikechukwu S., Okafor Ugochukwu U., Ajaghaku Amara A.   +5 more
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Utilisation des glucides et de leurs produits de métabolisme par Trypanosoma evansi et Trypanosoma brucei

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1964
Après avoir rappelé brièvement les connaissances actuelles sur le métabolisme glucidique de Trypanosoma evansi et Trypanosoma brucei, l'auteur expose les résultats obtenus par deux méthodes originales.
J. Balis
doaj   +1 more source

The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes

Molecules, 2022
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followed by
Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson   +10 more
doaj   +1 more source