Results 1 to 10 of about 32,780 (234)
Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice. [PDF]
PLoS One, 2019 Experiments on infections caused by trypanosomes are widely performed in Swiss white mice through various inoculation routes. To better understand the effect of route of trypanosome inoculation on disease outcomes in this model, we characterised the ...
Ndungu K +8 more
europepmc +2 more sources
Molecular Identification of ABC2 Transporter Gene Encode Protein Ngawi Trypanosoma evansi Isolate that suspected resistance to Isometamidium Chloride [PDF]
BIO Web of Conferences, 2021 This study aims to determine the profile of the ABC2 encoding transporter on Trypanosoma evansi (T. evansi) Ngawi isolates, Indonesia, exposed with Isometamidium Chloride (ISM). This study used blood samples of mice containing Trypanosoma evansi that had
Wusahaningtyas Lu’lu’ Sahara +4 more
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Wellcome Open Research, 2022 Background: Trypanosoma brucei is a protozoan parasite and the etiological agent of human and animal African trypanosomiasis. The organism cycles between its mammalian host and tsetse vector.
Michael A. J. Ferguson, Michele Tinti
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Trypanosoma brucei brucei is more pathogenic in rats compared to mice, making rats a better candidate for the relevant research studies [PDF]
The Iranian Journal of Veterinary Science and Technology, 2021 Trypanosomosis is an economically important disease that has raised great and diverse kinds of research using different types of animals. Hence, this study is aimed at determining the better laboratory animal between the Swiss albino mice and Wistar ...
Karimat Hussain +4 more
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Transport of -Aminoisobutyrate into Trypanosoma brucei brucei [PDF]
Microbiology, 1984 The uptake of alpha-aminoisobutyrate (AIB) by washed cell suspensions of bloodstream forms of Trypanosoma brucei brucei has been shown to be an energy-dependent process. No metabolism of AIB was detected under conditions leading to a 100-fold accumulation of AIB within the organism. Kinetic studies revealed that AIB uptake involved two components; that
K P, Coolbear, M, Midgley
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Clinical Phytoscience, 2020 Objective The present study investigated the anti-Trypanosoma brucei brucei activity of methanolic extract of Senna occidentalis roots, leaves, stem bark, and seed in vitro and bioactive components of the most active plant part.
Zainab Aliyu Alhafiz +4 more
doaj +1 more source
Therapeutic Strategies against Leishmania and Trypanosoma
Pathogens, 2023 Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (also known as Chagas disease, with Trypanosoma cruzi as the etiological
André L. S. Santos +5 more
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The exosome of Trypanosoma brucei [PDF]
The EMBO Journal, 2001 The yeast exosome is a complex of at least 10 essential 3'-5' riboexonucleases which is involved in 3'-processing of many RNA species. An exosome-like complex has been found or predicted to exist in other eukaryotes but not in Escherichia coli. The unicellular parasite Trypanosoma brucei diverged very early in eukaryotic evolution.
A M, Estévez, T, Kempf, C, Clayton
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Open Veterinary Science, 2022 This study investigated the antitrypanosomal activity of Argemone mexicana extract and fractions in the animal model of Trypanosoma brucei brucei infection.
Chukwu Ifeoma L. +5 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi +23 more
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