Results 21 to 30 of about 49,820 (224)
Structure of thioredoxin from Trypanosoma brucei brucei
FEBS Letters, 2003 The three‐dimensional structure of thioredoxin from Trypanosoma brucei brucei has been determined at 1.4 Å resolution. The overall structure is more similar to that of human thioredoxin than to any other thioredoxin structure. The most striking difference to other thioredoxins is the absence of a buried carboxylate behind the active site cysteines ...
Friemann, Rosmarie +5 more
openaire +2 more sources
Autoimmunity to phosphatidylserine and anemia in African Trypanosome infections.
PLoS Neglected Tropical Diseases, 2021 Anemia caused by trypanosome infection is poorly understood. Autoimmunity during Trypanosoma brucei infection was proposed to have a role during anemia, but the mechanisms involved during this pathology have not been elucidated. In mouse models and human
Juan Rivera-Correa +5 more
doaj +1 more source
Molecular epidemiology of African sleeping sickness [PDF]
, 2009 Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT +5 more
core +2 more sources
The Trypanosoma brucei AIR9-like protein is cytoskeleton-associated and is required for nucleus positioning and accurate cleavage furrow placement [PDF]
, 2012 AIR9 is a cytoskeleton-associated protein in Arabidopsis thaliana with roles in cytokinesis and cross wall maturation, and reported homologues in land plants and excavate protists, including trypanosomatids.
Almeida Costa, Cristina +7 more
core +3 more sources
International Journal for Parasitology: Drugs and Drug Resistance, 2015 Aquaglyceroporin-2 is a known determinant of melarsoprol–pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2–AQP3 tandem locus was described from melarsoprol–pentamidine cross-resistant ...
Fabrice E. Graf +5 more
doaj +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1964 Après avoir rappelé brièvement les connaissances actuelles sur le métabolisme glucidique de Trypanosoma evansi et Trypanosoma brucei, l'auteur expose les résultats obtenus par deux méthodes originales.
J. Balis
doaj +1 more source
Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis.
PLoS Pathogens, 2021 Human African Trypanosomiasis (HAT) has been responsible for several deadly epidemics throughout the 20th century, but a renewed commitment to disease control has significantly reduced new cases and motivated a target for the elimination of Trypanosoma ...
Alexandre Girard +16 more
doaj +1 more source
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. [PDF]
, 2013 OBJECTIVES: Trypanosoma brucei drug transporters include the TbAT1/P2 aminopurine transporter and the high-affinity pentamidine transporter (HAPT1), but the genetic identity of HAPT1 is unknown. We recently reported that loss of T.
Aguinaga Andrés, David +19 more
core +4 more sources
Parasites & Vectors, 2014 Background Human African Trypanosomiasis is still a public health threat in Cameroon. To assess Trypanosoma brucei strains circulating in the Fontem sleeping sickness focus, we conducted a genetic structure study using microsatellites to assess genotypes
Gustave Simo +5 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2021 Background Euphorbia is the largest genus in family Euphorbiaceae with a great biological and genetic diversity. The anti-trypanosomal activity of the crude extract of 15 Euphorbia species against Trypanosoma brucei brucei was carried out.
Seham S. El-Hawary +4 more
doaj +1 more source