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Identification of Potential Vectors and Species Density of Tsetse Fly, Prevalence, and Genetic Diversity of Drug-Resistant Trypanosomes in Kenya [PDF]
PathogensTsetse flies are major vectors of trypanosomes in Sub-Saharan Africa, posing risks to livestock and human health. This study investigated the diversity, distribution, and infection rates of tsetse species, as well as the genetic diversity of drug ...
Ivy S. Okello +4 more
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Frontiers in Cellular and Infection Microbiology, 2023 Chagas disease (CD) is a life-threatening illness caused by the parasite Trypanosoma cruzi (T. cruzi). With around seven million people infected worldwide and over 50,000 deaths per year, CD is a major public health issue in Latin America. The main route
Hellen Daghero +6 more
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Barcoding in trypanosomes [PDF]
Parasitology, 2017 SUMMARYTrypanosomes (genus Trypanosoma) are parasites of humans, and wild and domestic mammals, in which they cause several economically and socially important diseases, including sleeping sickness in Africa and Chagas disease in the Americas. Despite the development of numerous molecular diagnostics and increasing awareness of the importance of these ...
RACHEL HUTCHINSON, JAMIE R. STEVENS
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Parasitology, 2010 SUMMARYAfrican trypanosomes have emerged as promising unicellular model organisms for the next generation of systems biology. They offer unique advantages, due to their relative simplicity, the availability of all standard genomics techniques and a long history of quantitative research.
Bakker, B. +8 more
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Parasites & Vectors, 2019 African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most famous for their mechanisms of immune evasion by antigenic variation, there have been recent important studies that illuminate important aspects of the biology of these parasites both in ...
Cayla, Mathieu +4 more
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Presence of trypanosome species and anemic status of dogs in Zuru, Nigeria [PDF]
Macedonian Veterinary Review, 2015 The aim of this research is to study the presence and prevalence of trypanosome species in local dogs between January and July, 2010 in the Zuru area of Kebbi State, Nigeria.Standard trypanosome detection methods comprising of wet blood films, thin films
Rafi Rabecca Tono +5 more
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Systematic Review and Meta-Analysis on Human African Trypanocide Resistance
Pathogens, 2022 Background Human African trypanocide resistance (HATr) is a challenge for the eradication of Human African Trypansomiaisis (HAT) following the widespread emergence of increased monotherapy drug treatment failures against Trypanosoma brucei gambiense and ...
Keneth Iceland Kasozi +2 more
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Memorias do Instituto Oswaldo Cruz, 2002 The life cycle of Triatoma klugi Carcavallo, Jurberg, Lent & Galvão 2001 was compared under laboratory conditions using two groups of the F1 generation obtained from field-collected bugs.
Emmanuelle-Machado Priscilla +5 more
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The trypanosome flagellum [PDF]
Journal of Cell Science, 2003 African Trypanosomes are flagellated protozoan parasites that cause sleeping sickness in humans and Nagana in cattle. During its life cycle, Trypanosoma brucei alternates between an insect vector (tsetse fly) and a mammalian host.
Vaughan, S, Gull, K
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Trypanothione synthetase (TryS) produces N1,N8-bis(glutathionyl)spermidine (or trypanothione) at the expense of ATP. Trypanothione is a metabolite unique and essential for survival and drug-resistance of trypanosomatid parasites. In this study, we report
Andrea Medeiros +11 more
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