Results 11 to 20 of about 25,093 (176)

Replicative slender bloodstream forms complete transmission of Trypanosoma brucei without prior differentiation into stumpy forms [PDF]

open access: yeseLife
We have previously shown that the slender form of Trypanosoma (T.) brucei is able to infect teneral tsetse flies, develop to the first fly form, which is the procyclic form, and complete the life cycle in the insect vector (Schuster et al., 2021 ...
Carina Praisler   +6 more
doaj   +2 more sources

The exquisite mechanics of a tsetse bite [PDF]

open access: yeseLife
Specialized anatomical structures in the mouth and feet of tsetse flies help them feed on blood from a variety of hosts.
Katelyn Fealy, Álvaro Acosta-Serrano
doaj   +2 more sources

Validating Wing Biopsies for Blood-Borne Pathogen Characterization in Bats. [PDF]

open access: yesMol Ecol
ABSTRACT Wildlife surveillance is critical for tracking disease emergence, characterizing pathogen diversity, and assessing spillover risks. Blood‐borne pathogens are of particular interest for such efforts due to their global distribution, broad host taxa, and zoonotic potential.
Simonis MC   +9 more
europepmc   +2 more sources

Murine colon organoids as a novel model to study Trypanosoma cruzi infection and interactions with the intestinal epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Chagas disease (CD) is a life-threatening illness caused by the parasite Trypanosoma cruzi (T. cruzi). With around seven million people infected worldwide and over 50,000 deaths per year, CD is a major public health issue in Latin America. The main route
Hellen Daghero   +6 more
doaj   +1 more source

A molecular mechanism for eflornithine resistance in African trypanosomes [PDF]

open access: yes, 2010
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei.
Creek, Darren   +7 more
core   +5 more sources

Presence of trypanosome species and anemic status of dogs in Zuru, Nigeria [PDF]

open access: yesMacedonian Veterinary Review, 2015
The aim of this research is to study the presence and prevalence of trypanosome species in local dogs between January and July, 2010 in the Zuru area of Kebbi State, Nigeria.Standard trypanosome detection methods comprising of wet blood films, thin films
Rafi Rabecca Tono   +5 more
doaj   +1 more source

Systematic Review and Meta-Analysis on Human African Trypanocide Resistance

open access: yesPathogens, 2022
Background Human African trypanocide resistance (HATr) is a challenge for the eradication of Human African Trypansomiaisis (HAT) following the widespread emergence of increased monotherapy drug treatment failures against Trypanosoma brucei gambiense and ...
Keneth Iceland Kasozi   +2 more
doaj   +1 more source

Biology of Triatoma klugi Carcavallo, Jurberg, Lent & Galvão 2001 (Heteroptera: Reduviidae) under Laboratory Conditions: Effects of Distinct Blood Sources and Susceptibility to Trypanosoma cruzi and Trypanosoma rangeli

open access: yesMemorias do Instituto Oswaldo Cruz, 2002
The life cycle of Triatoma klugi Carcavallo, Jurberg, Lent & Galvão 2001 was compared under laboratory conditions using two groups of the F1 generation obtained from field-collected bugs.
Emmanuelle-Machado Priscilla   +5 more
doaj   +3 more sources

Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Trypanothione synthetase (TryS) produces N1,N8-bis(glutathionyl)spermidine (or trypanothione) at the expense of ATP. Trypanothione is a metabolite unique and essential for survival and drug-resistance of trypanosomatid parasites. In this study, we report
Andrea Medeiros   +11 more
doaj   +1 more source

Detection of Trypanosoma Infection in Dromedary Camels by Using Different Diagnostic Techniques in Northern Oman

open access: yesAnimals, 2022
Camel trypanosomoses is considered a devastating disease with severe health consequences that can be caused by different hemoprotozoan parasites. Camel samples (388) from the five regions in Northern Oman were assessed using a thin blood film.
Amal Al-Kharusi   +11 more
doaj   +1 more source

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