Results 31 to 40 of about 25,093 (176)

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

eLife, 2016
The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan parasites has been overlooked for decades as these pathogens have been regarded primarily as blood-dwelling organisms.
Paul Capewell, Christelle Cren-Travaillé, Francesco Marchesi, Pamela Johnston, Caroline Clucas, Robert A Benson, Taylor-Anne Gorman, Estefania Calvo-Alvarez, Aline Crouzols, Grégory Jouvion, Vincent Jamonneau, William Weir, M Lynn Stevenson, Kerry O'Neill, Anneli Cooper, Nono-raymond Kuispond Swar, Bruno Bucheton, Dieudonné Mumba Ngoyi, Paul Garside, Brice Rotureau, Annette MacLeod   +20 more
doaj   +1 more source

Shared species of crocodilian trypanosomes carried by tabanid flies in Africa and South America, including the description of a new species from caimans, Trypanosoma kaiowa n. sp.

Parasites & Vectors, 2019
Background The genus Trypanosoma Gruby, 1843 is constituted by terrestrial and aquatic phylogenetic lineages both harboring understudied trypanosomes from reptiles including an increasing diversity of crocodilian trypanosomes.
Bruno R. Fermino, Fernando Paiva, Laerte B. Viola, Carla M. F. Rodrigues, Herakles A. Garcia, Marta Campaner, Carmen S. A. Takata, Desie Sheferaw, John J. Kisakye, Agapitus Kato, Carlos A. G. S. Jared, Marta M. G. Teixeira, Erney P. Camargo   +12 more
doaj   +1 more source

Optical trapping reveals propulsion forces, power generation and motility efficiency of the unicellular parasites Trypanosoma brucei brucei [PDF]

, 2014
Unicellular parasites have developed sophisticated swimming mechanisms to survive in a wide range of environments. Cell motility of African trypanosomes, parasites responsible for fatal illness in humans and animals, is crucial both in the insect vector ...
Engstler, M., Heddergott, Niko, Engstler, Markus, Heddergott, N., Pfohl, T., Stellamanns, E., Hochstetter, Axel, Stellamanns, Eric, Pfohl, Thomas, Uppaluri, S., Uppaluri, Sravanti, Hochstetter, A., Hochstetter A, Engstler M, Heddergott N, Stellamanns E, Uppaluri S, Pfohl T   +17 more
core   +1 more source

Tissue tropism in parasitic diseases [PDF]

Open Biology, 2019
Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major cause of morbidity and mortality worldwide, but particularly in tropical, developing countries.
Sara Silva Pereira, Sandra Trindade, Mariana De Niz, Luisa M. Figueiredo   +3 more
doaj   +1 more source

Impact of Microscopic Motility on the Swimming Behavior of Parasites : Straighter Trypanosomes are More Directional [PDF]

, 2011
Microorganisms, particularly parasites, have developed sophisticated swimming mechanisms to cope with a varied range of environments. African Trypanosomes, causative agents of fatal illness in humans and animals, use an insect vector (the Tsetse fly) to ...
Nagler, J., Engstler, M., Heddergott, Niko, Sravanti Uppaluri, Herminghaus, Stephan, Pfohl, T., Heddergot, N., Stellamanns, E., Stephan Herminghaus, Pfohl, Thomas, Uppaluri, S., Herminghaus, S., Uppaluri, Sravanti, Markus Engstler, Engstler, Markus, Eric Stellamanns, Stellamanns, Eric, Jan Nagler, Niko Heddergott, Nagler, Jan, Thomas Pfohl, Engstler Markus, Nagler Jan, Pfohl Thomas, Herminghaus Stephan, Uppaluri Sravanti, Heddergott Niko, Stellamanns Eric   +27 more
core   +2 more sources

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

Frontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez, Cecilia Ortíz, Estefania Dibello, Estefania Dibello, Marcelo A. Comini   +4 more
doaj   +1 more source

Molecular Detection of Trypanosoma spp. in Questing and Feeding Ticks (Ixodidae) Collected from an Endemic Region of South-West Australia

Pathogens, 2021
A growing number of indigenous trypanosomes have been reported to naturally infect a variety of Australian wildlife with some species of Trypanosoma implicated in the population decline of critically endangered marsupials.
Anna-Sheree Krige, R. C. Andrew Thompson, Anke Seidlitz, Sarah Keatley, Julia Wayne, Peta L. Clode   +5 more
doaj   +1 more source

Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening

Frontiers in Chemical Biology
Trypanosoma cruzi is the etiologic agent of Chagas’ disease, a debilitating and mortal zoonotic illness that threatens the lives of several millions of people in the American continent. The acute phase is underdiagnosed and there is no curative treatment
Cristina Quiroga, Marcelo Incerti, Diego Benitez, Eduardo Manta, Andrea Medeiros, Andrea Medeiros, Marcelo A. Comini   +6 more
doaj   +1 more source

Blood and intestinal parasites of squirrels (Rodentia: Sciuridae) in Amazonian Brazil

Memorias do Instituto Oswaldo Cruz, 2004
We report the result of an examination for blood and intestinal protozoa in 12 specimens of the red squirrel Sciurus spadiceus (Rodentia: Sciuridae) from Birroque, municipality of Plácido de Castro, state of Acre, Brazil.
Ralph Lainson, Maria do Carmo de Oliveira Brígido, Fernando Tobias Silveira   +2 more
doaj   +1 more source

Cholesterol import fails to prevent catalyst-based inhibition of ergosterol synthesis and cell proliferation of Trypanosoma brucei

Journal of Lipid Research, 2007
Trypanosoma brucei (TB) cultured in rat blood, bovine serum, or lipid-depleted serum generated distinct differences in cholesterol availability. Whereas cell proliferation of the parasite was relatively unaffected by cholesterol availability, the ratios ...
Wenxu Zhou, George A.M. Cross, W. David Nes   +2 more
doaj   +1 more source