Results 21 to 30 of about 14,222 (187)

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

eLife, 2016
The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan parasites has been overlooked for decades as these pathogens have been regarded primarily as blood-dwelling organisms.
Paul Capewell, Christelle Cren-Travaillé, Francesco Marchesi, Pamela Johnston, Caroline Clucas, Robert A Benson, Taylor-Anne Gorman, Estefania Calvo-Alvarez, Aline Crouzols, Grégory Jouvion, Vincent Jamonneau, William Weir, M Lynn Stevenson, Kerry O'Neill, Anneli Cooper, Nono-raymond Kuispond Swar, Bruno Bucheton, Dieudonné Mumba Ngoyi, Paul Garside, Brice Rotureau, Annette MacLeod   +20 more
doaj   +1 more source

Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi

Molecules, 2016
Glucose-6-phosphate dehydrogenase (G6PDH) plays a housekeeping role in cell metabolism by generating reducing power (NADPH) and fueling the production of nucleotide precursors (ribose-5-phosphate).
Cecilia Ortiz, Francesca Moraca, Andrea Medeiros, Maurizio Botta, Niall Hamilton, Marcelo A. Comini   +5 more
doaj   +1 more source

Shared species of crocodilian trypanosomes carried by tabanid flies in Africa and South America, including the description of a new species from caimans, Trypanosoma kaiowa n. sp.

Parasites & Vectors, 2019
Background The genus Trypanosoma Gruby, 1843 is constituted by terrestrial and aquatic phylogenetic lineages both harboring understudied trypanosomes from reptiles including an increasing diversity of crocodilian trypanosomes.
Bruno R. Fermino, Fernando Paiva, Laerte B. Viola, Carla M. F. Rodrigues, Herakles A. Garcia, Marta Campaner, Carmen S. A. Takata, Desie Sheferaw, John J. Kisakye, Agapitus Kato, Carlos A. G. S. Jared, Marta M. G. Teixeira, Erney P. Camargo   +12 more
doaj   +1 more source

Tissue tropism in parasitic diseases [PDF]

Open Biology, 2019
Parasitic diseases, such as sleeping sickness, Chagas disease and malaria, remain a major cause of morbidity and mortality worldwide, but particularly in tropical, developing countries.
Sara Silva Pereira, Sandra Trindade, Mariana De Niz, Luisa M. Figueiredo   +3 more
doaj   +1 more source

Molecular Detection of Trypanosoma spp. in Questing and Feeding Ticks (Ixodidae) Collected from an Endemic Region of South-West Australia

Pathogens, 2021
A growing number of indigenous trypanosomes have been reported to naturally infect a variety of Australian wildlife with some species of Trypanosoma implicated in the population decline of critically endangered marsupials.
Anna-Sheree Krige, R. C. Andrew Thompson, Anke Seidlitz, Sarah Keatley, Julia Wayne, Peta L. Clode   +5 more
doaj   +1 more source

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasis

Frontiers in Chemical Biology
IntroductionIn vivo imaging technology based on bioluminescence has contributed to the study of different pathophysiological conditions involving inherited or transmissible diseases.
Diego Benítez, Cecilia Ortíz, Estefania Dibello, Estefania Dibello, Marcelo A. Comini   +4 more
doaj   +1 more source

Development of bioluminescent reporter Trypanosoma cruzi and bioassay for compound screening

Frontiers in Chemical Biology
Trypanosoma cruzi is the etiologic agent of Chagas’ disease, a debilitating and mortal zoonotic illness that threatens the lives of several millions of people in the American continent. The acute phase is underdiagnosed and there is no curative treatment
Cristina Quiroga, Marcelo Incerti, Diego Benitez, Eduardo Manta, Andrea Medeiros, Andrea Medeiros, Marcelo A. Comini   +6 more
doaj   +1 more source

Blood and intestinal parasites of squirrels (Rodentia: Sciuridae) in Amazonian Brazil

Memorias do Instituto Oswaldo Cruz, 2004
We report the result of an examination for blood and intestinal protozoa in 12 specimens of the red squirrel Sciurus spadiceus (Rodentia: Sciuridae) from Birroque, municipality of Plácido de Castro, state of Acre, Brazil.
Ralph Lainson, Maria do Carmo de Oliveira Brígido, Fernando Tobias Silveira   +2 more
doaj   +1 more source

Cytokinesis in trypanosomes

Cytoskeleton, 2012
AbstractCytokinesis is a crucial step in the cell division cycle whereby the cell membrane and underlying cortex is remodelled and drawn together to create two new daughter cells. While in many eukaryotic systems this process is accomplished by an actomyosin contractile ring, the protozoan parasite Trypanosoma brucei displays an unusual mechanism for ...
Farr, H, Gull, K
openaire   +3 more sources

Trypanosome Glycosylphosphatidylinositol Biosynthesis [PDF]

The Korean Journal of Parasitology, 2009
Trypanosoma brucei, a protozoan parasite, causes sleeping sickness in humans and Nagana disease in domestic animals in central Africa. The trypanosome surface is extensively covered by glycosylphosphatidylinositol (GPI)-anchored proteins known as variant surface glycoproteins and procyclins.
Yeonchul, Hong, Taroh, Kinoshita
openaire   +2 more sources