Results 31 to 40 of about 32,780 (234)

Population genetics of Trypanosoma brucei circulating in Glossina palpalis palpalis and domestic animals of the Fontem sleeping sickness focus of Cameroon

Parasites & Vectors, 2014
Background Human African Trypanosomiasis is still a public health threat in Cameroon. To assess Trypanosoma brucei strains circulating in the Fontem sleeping sickness focus, we conducted a genetic structure study using microsatellites to assess genotypes
Gustave Simo, Guy Roger Njitchouang, Tresor Tito Tanekou Melachio, Flobert Njiokou, Gerard Cuny, Asonganyi Tazoacha   +5 more
doaj   +1 more source

P-type transport ATPases in Leishmania and Trypanosoma

Parasite, 2019
P-type ATPases are critical to the maintenance and regulation of cellular ion homeostasis and membrane lipid asymmetry due to their ability to move ions and phospholipids against a concentration gradient by utilizing the energy of ATP hydrolysis.
Meade John C.
doaj   +1 more source

Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition. [PDF]

PLoS ONE, 2010
BACKGROUND: The 14-3-3 proteins are structurally conserved throughout eukaryotes and participate in protein kinase signaling. All 14-3-3 proteins are known to bind to evolutionally conserved phosphoserine-containing motifs (modes 1 and/or 2) with high ...
Masahiro Inoue, Kouichi Yasuda, Haruki Uemura, Natsumi Yasaka, Hiroshi Inoue, Yoshitatsu Sei, Nobuo Horikoshi, Toshihide Fukuma   +7 more
doaj   +1 more source

The exopolyphosphatase TbrPPX1 of Trypanosoma brucei [PDF]

BMC Microbiology, 2011
Abstract Background Exopolyphosphatases and pyrophosphatases play important but still incompletely understood roles in energy metabolism, and also in other aspects of cell biology such as osmoregulation or signal transduction.
Luginbuehl, Edith, Kunz, Stefan, Wentzinger, Laurent, Freimoser, Florian, Seebeck, Thomas   +4 more
openaire   +5 more sources

The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic Human African Trypanosomiasis [PDF]

, 2010
<p><b>Background:</b> <i>Trypanosoma brucei gambiense</i> is the causative agent of chronic Human African Trypanosomiasis or sleeping sickness, a disease endemic across often poor and rural areas of Western and Central ...
Martin A Aslett, Hertz-Fowler Christiane, Chukualim, B., Gibson, W., Melville, S.E., Jackson Andrew P., Jackson, A.P., Jackson, A., Capewell, P., Sanders Mandy, Annette MacLeod, McQuillan, J, Quail, M.A., MacLeod Annette, Melville Sara E., Melville, S., McQuillan, J., Paul Capewell, Aslett Martin A., Bridget Chukualim, MacLeod, A., Aslett, M., Hertz-Fowler, C., McQuillan Jacqueline, Aslett, M.A., Mandy Sanders, Berry Andrew, Michael A Quail, Barry, J.D., Berriman, M., Sanders, M., Wendy Gibson, Sara E Melville, Jacqueline McQuillan, Gibson, WC, Quail Michael A., Berry, A., J David Barry, Andrew P Jackson, Andrew Berry, Christiane Hertz-Fowler, Matthew Berriman, Chukualim Bridget, Gibson Wendy, Barry J. David, Capewell Paul, Berriman Matthew   +46 more
core   +1 more source

SUMOylation in Trypanosoma brucei

PeerJ, 2013
Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins. The levels of SUMOylation were unaffected by temperature changes but were increased by severe oxidative stress.
Klein, Cornelia Andrea, Droll, Dorothea, Clayton, Christine   +2 more
openaire   +4 more sources

Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty. [PDF]

, 2015
Two key biological features distinguish Trypanosoma evansi from the T. brucei group: independence from the tsetse fly as obligatory vector, and independence from the need for functional mitochondrial DNA (kinetoplast or kDNA).
Hideo Imamura (62469), Dhileep Sivam, Myler, Peter, Ivens Alasdair, McDermott, Suzanne M., Sivam Dhileep, Ramasamy, Gowthaman, Lukeš Julius, Kořený Luděk, Schnaufer, Achim, Michael Lewis (339161), Chris Merritt (682366), Severine Monnerat (3278655), De-Hua Lai, Brown, Rob, Claire Gendrin, Balmer Oliver, Merritt, Chris, Andrew Jackson, Monnerat Severine, Michael Lewis, Lun, Zhao Rong, Hideo Imamura, Wonjong Moon, Stuart, Ken, Isabelle Phan, Marc Desquesnes, Jackson, Andrew, Myler Peter, Balmer, Olivier, Alasdair Ivens, Gowthaman Ramasamy (19191), Schnaufer, Achim; id_orcid, McDermott Suzanne M., Carnes Jason, Ivens, Alasdair, Peter Myler (592207), Phan, Isabelle, Lukeš, Julius, Lun, Zhao-Rong, Lai, De Hua, Jason Carnes, Imamura Hideo, Lai De-Hua, Balmer, Oliver, Alasdair Ivens (33327), Gendrin, Claire, Lai, De-Hua, Gendrin Claire, Desquesnes, Marc, Julius Lukeš, Anupama, Atashi, Cestari, Igor, Zhao-Rong Lun, Chris Merritt, Cestari Igor, Suzanne M. McDermott (436260), Ken Stuart, Isabelle Phan (5674), Brown Rob, Peter Myler, Jackson Andrew, Suzanne M McDermott, Igor Cestari (251742), Hertz-Fowler Christiane, Rob Brown (682364), Monnerat, Severine, Julius Lukeš (122896), Lewis, Michael, Imamura, Hideo, McDermott, Suzanne M, Annette MacLeod, Stuart Ken, MacLeod Annette, Severine Monnerat, MacLeod, Annette, Anupama Atashi, Luděk Kořený (240382), Gowthaman Ramasamy, Achim Schnaufer (243262), Desquesnes Marc, Zhao-Rong Lun (104756), Ramasamy Gowthaman, Achim Schnaufer, Merritt Chris, Sivam, Dhileep, Andrew Jackson (376958), Luděk Kořený, Dhileep Sivam (682368), Hertz-Fowler, Christiane, Moon, Wonjong, Wonjong Moon (682367), Oliver Balmer, Moon Wonjong, Lewis Michael, Jason Carnes (47297), Atashi Anupama (682363), Lun Zhao-Rong, Phan Isabelle, Ken Stuart (682369), Igor Cestari, Oliver Balmer (151993), Claire Gendrin (173845), Kořený, Luděk, Atashi Anupama, Carnes, Jason, Annette MacLeod (12779), Christiane Hertz-Fowler, Marc Desquesnes (457900), Christiane Hertz-Fowler (243178), Rob Brown, Schnaufer Achim, De-Hua Lai (682365)   +112 more
core   +1 more source

Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi. [PDF]

, 2007
BACKGROUND: Trypanosomes are parasitic protozoa that diverged early from the main eukaryotic lineage. Their genomes display several unusual characteristics and, despite completion of the trypanosome genome projects, the location of centromeric DNA has ...
Bot, Christopher, Nilsson, D,, Nilsson, Daniel, Andersson, B,, Andersson, Bjorn, Bot, C,, Obado, SO, Obado, Samson O, Kelly, JM, Kelly, John M   +9 more
core   +1 more source

Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis

Microbial Cell, 2014
Most African trypanosomes, including the veterinary species Trypanosoma brucei brucei and T. congolense are susceptible to lysis by human serum. A recent study by Alsford et al. [PLoS Pathogens (2014) 10, e1004130] has identified a T. b. brucei lysosomal
Sam Alsford
doaj   +1 more source

Identification of novel components of Trypanosoma brucei editosomes [PDF]

, 2003
The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Schnaufer, Achim; id_orcid, Wang, Bingbing, Salavati, Reza, Stuart, Kenneth, Carmean, Nicole, Panigrahi, Aswini K, Ernst, Nancy L   +6 more
core   +1 more source