Results 31 to 40 of about 22,441 (186)

Resolving Trypanosoma brucei Flagellar Structure by Cryo-Electron Tomography [PDF]

E3S Web of Conferences, 2019
Trypanosoma brucei is a unicellular eukaryote that can cause human African trypanosomiasis, which has continued to evolve and spread. The key feature of these parasites is that they have a flagellum consists of a typical 9 + 2 axoneme and a lattice-like ...
Dai Jennifer
doaj   +1 more source

Development of a camelid single-domain antibody-based antigen detection assay for the pan-specific diagnosis of active human and animal Trypanosoma brucei infections

Journal of Clinical Microbiology
Trypanosoma brucei infections cause African trypanosomiasis, also known as sleeping sickness in humans and nagana in animals, presenting a significant global health and economic burden, especially in sub-Saharan Africa.
Zeng Li, Bo-kyung Jin, Emily Estefania Timaury Moreno, Andrés Álvarez-Rodríguez, Jo A. Van Ginderachter, Magdalena Radwanska, Yann G. -J. Sterckx, Benoit Stijlemans, Stefan Magez   +8 more
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Analytical purification of a 60-kDa target protein of artemisinin detected in Trypanosoma brucei brucei

Data in Brief, 2015
Here we describe the isolation and purity determination of Trypanosoma brucei (T. b.) brucei candidate target proteins of artemisinin. The candidate target proteins were detected and purified from their biological source (T. b.
Benetode Konziase
doaj   +1 more source

Réponse du poulet nigérian local ( Gallus domesticus) aux trypanosomes

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
La réponse du poulet nigérian local aux souches de Trypanosoma brucei 8/18 et T. vivax Y58 a été recherchée. Le poulet local utilisé dans cette étude était sensible à T. brucei mais réfractaire à T. vivax (Y58) (une souche adaptée aux rongeurs).
O.A. Dina, R.O.A. Arowolo
doaj   +1 more source

Measure of Molecular Diversity within the Trypanosoma brucei Subspecies Trypanosoma brucei brucei and Trypanosoma brucei gambiense as Revealed by Genotypic Characterization

Experimental Parasitology, 2001
We have evaluated whether sequence polymorphisms in the rRNA intergenic spacer region can be used to study the relatedness of two subspecies of Trypanosoma brucei. Thirteen T. brucei isolates made up of 6 T. b. brucei and 7 T. b. gambiense were analyzed using restriction fragment length polymorphism (RFLP).
Agbo, E.C., Majiwa, P.A.O., Classsen, E.J.H.M., Roos, M.H.   +3 more
openaire   +3 more sources

In vitro Anti-trypanosomal Activity of Ethanolic and n-Hexane Extracts of Hymenocardia acida Stem Bark against Trypanosoma brucei brucei and Trypanosoma congolense

UMYU Journal of Microbiology Research
The development of resistance by trypanosomes to existing trypanocidal drugs necessitates the need to search for safer and more effective alternative drugs with a broad spectrum of activity.
Lawal, S. M., Inabo, H. I., Ella, E. E., Okubanjo, O. O.   +3 more
doaj   +1 more source

Genetic control of resistance to Trypanosoma brucei brucei infection in mice. [PDF]

PLoS Neglected Tropical Diseases, 2011
BackgroundTrypanosoma brucei brucei infects livestock, with severe effects in horses and dogs. Mouse strains differ greatly in susceptibility to this parasite.
Matyáš Síma, Helena Havelková, Lei Quan, Milena Svobodová, Taťána Jarošíková, Jarmila Vojtíšková, Alphons P M Stassen, Peter Demant, Marie Lipoldová   +8 more
doaj   +1 more source

The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes

Molecules, 2022
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followed by
Samya S. Alenezi, Naif D. Alenezi, Godwin U. Ebiloma, Manal J. Natto, Marzuq A. Ungogo, John O. Igoli, Valerie A. Ferro, Alexander I. Gray, James Fearnley, Harry P. de Koning, David G. Watson   +10 more
doaj   +1 more source

Golgi-associated phosphohydrolases in Trypanosoma brucei brucei

Molecular and Biochemical Parasitology, 1997
Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity).
Grab, D.J., Webster, P., Verjee, Y., Lonsdale-Eccles, J.   +3 more
openaire   +3 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source