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Human African trypanosomiasis

Infectious Disease Clinics of North America, 2012
Abstract Human African trypanosomiasis (sleeping sickness) is caused by subspecies of the protozoan parasite Trypanosoma brucei. The disease is restricted to tropical Africa where it is transmitted by the bite of infected tsetse flies (Glossina spp.).
Brun, R., Blum, J.
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African Trypanosomiasis

2022
African trypanosomiasis is caused by salivarian trypanosomes that are extracellular parasites affecting humans, livestock and game animals around the world. There are only three salivarian trypanosomes that can infect humans. Both Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense cause human African trypanosomosis (HAT) or ‘sleeping ...
Stefan, Magez   +3 more
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Human African Trypanosomiasis

2003
Human African trypanosomiasis (HAT) is caused by infestation with a flagellate protozoan, the trypanosome which is inoculated by the bite of the tsetse fly Glossina. The particular ecological conditions of parasites and vectors are such that the disease is only found in the intertropical regions of Africa.
M Dumas, B Bouteille
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African trypanosomiasis

Annals of Tropical Medicine & Parasitology, 2006
Trypanosomiasis remains one of the most serious constraints to economic development in sub-Saharan Africa and, as a consequence, related research has been subject to strong social and political as well as scientific influences. The epidemics of sleeping sickness that occurred at the turn of the 20th Century focussed research efforts on what became ...
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Chemotherapy of African trypanosomiasis

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1976
No new effective drugs for trypanosomiasis, human or animal, have been brought into field use for 20 years; increased drug development costs, the generally small drug budgets of developing countries and widespread evolution of drug resistance are primary causes.
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Pathology of African trypanosomiasis

1999
African sleeping sickness is characterized by a number of distinct neurological symptoms, which include dysaesthesia, extrapyramidal motor disturbances, disruption of sleep, as well as neuropsychiatric changes including mood disturbances which could represent the initial symptoms (see other chapters in this volume).
Kristensson K.   +1 more
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Immunobiology of African Trypanosomiasis

1984
African trypanosomes are flagellated Protozoa that include the causative agents of important human and animal diseases (Table I) and are fascinating biologically.
Margaret Pinder, G. E. Roelants
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African Trypanosomiasis

1994
Publisher Summary This chapter describes African trypanosomes as protozoan parasites that cause disease in humans and livestock. Both Trypanosoma brucei rhodesiense and T. brucei gambiense cause sleeping sickness in humans. Tsetse flies only occur in Africa and Saudi Arabia.
Jan Naessens   +4 more
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Human African trypanosomiasis

The Lancet
Human African trypanosomiasis or sleeping sickness is caused by infection with Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense parasites, which are transmitted by tsetse flies in sub-Saharan Africa. Control of human African trypanosomiasis is based on case detection, treatment, and vector control.
Veerle, Lejon   +2 more
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