Results 31 to 40 of about 1,974 (222)
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Book review: learning from the curse: Sembene's Xala by Richard Fardon and Senga la Rouge [PDF]
Dagna Rams highlights the many uses of ‘Learning from the curse’: a fun and off-beat reportage of the place and the time, a film club companion for solitary viewers, and also a book to admire ...
Rams, Dagna
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
This work is a review essay of two books: Africanity Redefined: Collected Essays of Ali A. Mazrui, edited by Ali Alamin Mazrui, Ricardo Rene Laremont, Tracia Leacock Seghatolislami, Michael A.
Paul Banahene Adjei
doaj +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Christina Landman is a professor of Theology at the Research Institute for Theology and Religion, University of South Africa. As an East African serving under her as a research fellow at the Research Institute of Theology and Religion since 2014, and as ...
Julius M. Gathogo
doaj +1 more source
Politics and street trading in Africa: Developing a comparative frame. [PDF]
Street trading is ubiquitous in African cities, but despite research over the last 40 years, there has been relatively little analysis of the political factors that influence the street economy.
Brown, Alison, Mackie, Peter
core +3 more sources
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Paul Verdu introduces the anthropology and genetics of African populations often summarised under the label 'Pygmy'.
openaire +3 more sources

