Results 41 to 50 of about 3,663 (249)
Remember Death: An Examination of Death, Mourning, and Death Anxiety Within Islam
Open Theology, 2022 Scholarship and research in the field of thanatology require creative responses to address contemporary concerns regarding how people – individually and collectively – make sense of events and experiences associated with death and dying.
Davoudi Nilou
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Kur’ân ve Tenasüh Tartışmaları: Bağlam ve Deliller Üzerine Bir İnceleme
İlahiyat AkademiBu çalışma, Kur’an’da yer alan bazı ayetlerin tenasüh (reenkarnasyon) inancını desteklediği yönünün savunulması ve bu iddiaların Kur’an’ın teolojik ve bağlamsal bütünlüğü içerisinde değerlendirilmesini konu almaktadır.
Özer Baş, İbrahim Halil Erdoğan
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ölüm Ötesi İnancının Bilişsel Açıklamalarının Eleştirel Bir Analizi
Cumhuriyet İlahiyat Dergisi, 2020 The Cognitive Science of Religion (CSR) is a scientific approach to the study of religion that seeks to provide causal explanations of religious beliefs and practices.
Mahdi Biabanaki
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Journal of Travel Medicine, 2019 Antibiotics have an afterlife. They remain biologically active and affect microbial ecosystems in and outside the body. Antibiotics used by humans and animals are excreted and reach the environment through multiple pathways causing widespread contamination of soil and water globally.
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source