Results 51 to 60 of about 30,636 (221)
FluidsThe interaction between the left ventricle (LV) and aorta is critical for cardiovascular performance, particularly under pathophysiological conditions. However, how changes in LV mechanics, including preload and afterload, affect aortic function via LV ...
Chenghan Cai, Ge He, Lei Fan
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PLoS ONE, 2019 BackgroundWomen have a greater risk of heart failure with preserved ejection fraction (HFPEF) than men do, yet the basis for this disparity remains unclear.
Hidemi Sorimachi +8 more
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The right ventricle in pulmonary arterial hypertension [PDF]
European Respiratory Review, 2014 Pulmonary arterial hypertension (PAH) is a right heart failure syndrome. In early-stage PAH, the right ventricle tends to remain adapted to afterload with increased contractility and little or no increase in right heart chamber dimensions.
Robert Naeije , Alessandra Manes
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Artificial Organs, EarlyView.Shear‐induced blood damage—including hemolysis, platelet and neutrophil injury, and von Willebrand factor (vWF) degradation—was evaluated for the BrioVAD and HM3 using an in vitro circulatory loop under clinically relevant conditions. Across 15 biomarkers (n > 6 per group), no significant differences were observed between the two devices.
Wenji Sun +9 more
wiley +1 more source
Cardiotoxicity of BRAF/MEK inhibitors
British Journal of Pharmacology, EarlyView.Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys +14 more
wiley +1 more source
Journal of Health Science and Medical Research (JHSMR), 2003 Shock is a syndrome of poor tissue perfusion that causes imbalance of oxygen demand and oxygen supply. Delayed diagnosis and treatment of shock may increase morbidity and mortality of the patients.
R Bhurayanontachai
doaj
Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review
British Journal of Pharmacology, EarlyView.Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß +3 more
wiley +1 more source
Left Ventricular Diastolic Dysfunction and Transcatheter Aortic Valve Replacement Outcomes: A Review
Cardiology and Therapy, 2019 Aortic stenosis (AS) is the most common valvular disease that can lead to increased afterload, left ventricular (LV) remodeling, and myocardial fibrosis. We reviewed the literature addressing the impact of transcatheter aortic valve replacement (TAVR) on
Seyed Hossein Aalaei-Andabili +1 more
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Problem Is in the Subclinical Afterload Mismatch [PDF]
Journal of Cardiovascular Ultrasound, 2012 REFER TO THE PAGE 79-84 In the era of aging society, prevalence of degenerative aortic stenosis (AS) increases rapidly.1) Systolic hypertension and widening of pulse pressure due to stiffened aorta are pathognomonic phenomenon in the elderly population.2) Compared to previous decades, echocardiographic evaluation of aortic valve become more ...
openaire +2 more sources