Results 71 to 80 of about 30,636 (221)

Determinants of left ventricular ejection fraction and a novel method to improve its assessment of myocardial contractility

Annals of Intensive Care, 2019
Background The aim of this study was to quantify the impact of different cardiovascular factors on left ventricular ejection fraction (LVEF) and test a novel LVEF calculation considering these factors. Results 10 pigs were studied.
Manuel Ignacio Monge García, Zhongping Jian, Jos J. Settels, Charles Hunley, Maurizio Cecconi, Feras Hatib, Michael R. Pinsky   +6 more
doaj   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Intrinsic mechanisms of right ventricular autoregulation

Scientific Reports
To elucidate the adaptation of the right ventricle to acute and intermittently sustained afterload elevation, targeted preload reductions and afterload increases were implemented in a porcine model involving 12 pigs.
Jan-Pit Meinert-Krause, Mare Mechelinck, Marc Hein, Moriz A. Habigt   +3 more
doaj   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

The Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista, Nathanael D. Herrera, Marcial Quiroga‐Carmona, Chandrasekhar Natarajan, Adriana Rico‐Cernohorska, Jorge Salazar Bravo, Graham R. Scott, Guillermo D'Elía, Zachary A. Cheviron, Jay F. Storz   +9 more
wiley   +1 more source

Heart-Lung interactions

Journal of Mechanical Ventilation
Background Heart-lung interactions represent a fundamental physiological relationship that determines the hemodynamic and respiratory responses in both healthy and critically ill patients.
Chacón-Lozsán Francisco
doaj   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier, Elliott J. Jenkins, Andrew Douglas, Jack Talbot, Alexandra Williams, Jonathan Moore, Craig D. Steinback, Liam D. Corr, Zoe H. Adams, Fabio Giuseppe Laginestra, Markus Amann, Philip N. Ainslie, Travis D. Gibbons, Mike Stembridge   +13 more
wiley   +1 more source

Prognostic implication of right ventricular-pulmonary artery coupling in valvular heart disease

Frontiers in Cardiovascular Medicine
Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RV–PA) coupling integrates the ability of RV contractility to adapt to ...
Zhenni Wu, Zhenni Wu, Zhenni Wu, Mingxing Xie, Mingxing Xie, Mingxing Xie, Li Zhang, Li Zhang, Li Zhang, Qing He, Qing He, Qing He, Lang Gao, Lang Gao, Lang Gao, Mengmeng Ji, Mengmeng Ji, Mengmeng Ji, Yixia Lin, Yixia Lin, Yixia Lin, Yuman Li, Yuman Li, Yuman Li   +23 more
doaj   +1 more source

Ultrasound‐based haemodynamic force trajectories in a murine model of reversible pressure overload

The Journal of Physiology, EarlyView.
Abstract figure legend High‐resolution ultrasound anatomical imaging and speckle‐tracking analysis were used to compute left ventricular (LV) haemodynamic forces (HDF) in a murine model of transverse aortic constriction (TAC) followed by aortic debanding (deTAC).
Peyton M. Day, Thomas Moore‐Morris, Craig J. Goergen, Pierre Sicard   +3 more
wiley   +1 more source