Results 81 to 90 of about 30,636 (221)
Background Afterload mismatch (AM) refers to high-gradient (mean gradient ≥40 mm Hg) severe aortic stenosis (AS) with reduced left ventricular ejection fraction (LVEF <50%) that is hypothesised to arise from mechanisms other than true contractile ...
Anton Doubell +2 more
doaj +1 more source
Presentation of preload and afterload to isolated heart preparations
Abstract figure legend The heart can be isolated, and when this is so, it must be subjected to loading conditions. Over the past few decades, various loading methods have been developed to prescribe preload and afterload to isolated working‐heart preparations.
Esau Mhandu +4 more
wiley +1 more source
Abstract Amniotic fluid embolism is a rare syndrome characterized by sudden cardiorespiratory collapse during labor or soon after delivery. Because of its rarity, many obstetrical providers have no experience in managing amniotic fluid embolism and may therefore benefit from a cognitive aid such as a checklist.
Society for Maternal‐Fetal Medicine (SMFM) +6 more
wiley +1 more source
This study analyzes the myocardial force-generating capacity in infective endocarditis (IE) using an experimental model of isolated human atrial myocardium.
Buschmann Katja +6 more
doaj +1 more source
Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed +7 more
wiley +1 more source
ABSTRACT Aortic stenosis (AS) is associated with a heightened burden of cardiovascular comorbidities, atrial fibrillation (AF), and progressive valvular calcification, all of which may contribute to cerebrovascular events across the disease continuum.
Priyanka Boettger +7 more
wiley +1 more source
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger +3 more
wiley +1 more source
Placental ischemia in pre‐eclampsia initiates cytokine‐driven endothelial dysfunction, angiogenic imbalance, oxidative stress, and thromboinflammation. Elevated TNF‐α, IL‐6, IL‐17, sFlt‐1, and complement activation promote vasoconstriction, thrombosis, and cardiovascular instability.
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Compared to traditional cardiometabolic comorbidities, COPD and atrial fibrillation are uniquely linked to pulmonary vascular remodeling in HFpEF. The impact of these two comorbidities on pulmonary vascular‐left atrial axis is highlighted by the shared biventricular morphology among HFpEF subgroups.
Mariana Garcia‐Arango +20 more
wiley +1 more source
Assessment of Pulmonary Vascular Impedance in Patients With Severe Pulmonary Arterial Hypertension
Pulmonary vascular impedance (PVZ) was calculated from clinical PA pressure and RVOT flow velocity profiles. Participants with increased pulmonary vascular resistance have increased PVZ, afterload, and diastolic stiffness. The characteristic impedance (ZC) to mean PA pressure relationship models the effect of proximal vasculature remodeling on ZC for a
Keeley Shea Ravellette +7 more
wiley +1 more source

