Results 101 to 110 of about 28,912 (281)

Katecheza podstawą rozwoju agape według Klemensa Aleksandryjskiego

open access: yesVox Patrum, 1990
Titus Flavius Clemens war ein hervorragender Vertreter der katechetlschen Schule in Alezandrien.
Józef Grzywaczewski
doaj  

The Threefold Nature of Desire and Its Implications for Ethics and Theology

open access: yesReligions
The study distinguishes three principal forms of desire: bodily desires, desires for perfection, and desires entailed in value-responses. By distinguishing between the self-centered, acquisitive desires for perfection and the inherently self-transcending
Martin Cajthaml
doaj   +1 more source

Detecting planets around stars in nearby galaxies

open access: yes, 1999
The only way to detect planets around stars at distances of several kpc is by (photometric or astrometric) microlensing observations. In this paper, we show that the capability of photometric microlensing extends to the detection of signals caused by ...
Covone, G.   +3 more
core   +1 more source

Faith, Librarianship and Technology

open access: yes, 2009
Technology is transforming many venues. Some suggest that the transformation is happening much too quickly, others suggest not quickly enough. As Christians, we have a responsibility to observe this technological transformation through the lens of faith ...
Trott, Garrett B.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Agapes rituelles

open access: yesDiasporas, 2005
Des Rochettes Jacqueline. Agapes rituelles. In: Diasporas. Histoire et sociétés, n°7, 2005. Cuisines en partage. pp. 165-166.
openaire   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A Challenging Conversation on Integral Futures: Embodied Foresight and Trialogues [PDF]

open access: yes, 2008
Practitioner reflection is vital for knowledge frameworks such as Ken Wilber's Integral perspective. Richard Slaughter, Joseph Voros and others have combined Wilber's perspective and Futures Studies to create Integral Futures as a new stance.
Burns, Alex, Floyd, Josh, Ramos, Jose
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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